Gene Symbol |
ENDOU
|
Entrez Gene |
8909
|
Alt Symbol |
P11, PP11, PRSS26
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
endonuclease, polyU-specific
|
Other Description |
22 serine protease|26 serine protease|placental protein 11|poly(U)-specific endoribonuclease|protein endoU|uridylate-specific endoribonuclease
|
Swissprots |
Q2NKJ4 B7Z6E1 P21128 B2RBJ3 B3KQS7
|
Accessions |
EAW57940 EAW57941 P21128 AI039727 AK075446 BAG52139 AK295963 BAH12230 AK300169 BAH13227 AK302308 BAH13670 AK314688 BAG37240 AX772808 CAE06253 BC069698 BC069715 AAH69715 BC074763 AAH74763 BC111782 AAI11783 DA838842 DA841959 DC381238 M32402 AAA36464 M36109 AAA36465 NM_001172439 NP_001165910 NM_001172440 NP_001165911 NM_006025 NP_006016
|
Function |
Endoribonuclease that cleaves single-stranded RNAs at uridylates and releases products that have 2'-3'-cyclic phosphate termini. {ECO:0000269|PubMed:18936097}.
|
Subcellular Location |
Secreted {ECO:0000305}.
|
Tissue Specificity |
Placental-specific, but also associated with various malignant neoplasms.
|