Gene Symbol | ENDOU |
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Entrez Gene | 8909 |
Alt Symbol | P11, PP11, PRSS26 |
Species | Human |
Gene Type | protein-coding |
Description | endonuclease, polyU-specific |
Other Description | 22 serine protease|26 serine protease|placental protein 11|poly(U)-specific endoribonuclease|protein endoU|uridylate-specific endoribonuclease |
Swissprots | Q2NKJ4 B7Z6E1 P21128 B2RBJ3 B3KQS7 |
Accessions | EAW57940 EAW57941 P21128 AI039727 AK075446 BAG52139 AK295963 BAH12230 AK300169 BAH13227 AK302308 BAH13670 AK314688 BAG37240 AX772808 CAE06253 BC069698 BC069715 AAH69715 BC074763 AAH74763 BC111782 AAI11783 DA838842 DA841959 DC381238 M32402 AAA36464 M36109 AAA36465 NM_001172439 NP_001165910 NM_001172440 NP_001165911 NM_006025 NP_006016 |
Function | Endoribonuclease that cleaves single-stranded RNAs at uridylates and releases products that have 2'-3'-cyclic phosphate termini. {ECO:0000269|PubMed:18936097}. |
Subcellular Location | Secreted {ECO:0000305}. |
Tissue Specificity | Placental-specific, but also associated with various malignant neoplasms. |
PP11 CRISPR/Cas9 KO Plasmid (h) - sc-411226 from Santa Cruz Biotechnology
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PP11 HDR Plasmid (h) - sc-411226-HDR from Santa Cruz Biotechnology
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PP11 Double Nickase Plasmid (h) - sc-411226-NIC from Santa Cruz Biotechnology
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PP11 Double Nickase Plasmid (h2) - sc-411226-NIC-2 from Santa Cruz Biotechnology
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PP11 CRISPR Activation Plasmid (h) - sc-411226-ACT from Santa Cruz Biotechnology
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PP11 CRISPR Activation Plasmid (h2) - sc-411226-ACT-2 from Santa Cruz Biotechnology
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PP11 Lentiviral Activation Particles (h) - sc-411226-LAC from Santa Cruz Biotechnology
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PP11 Lentiviral Activation Particles (h2) - sc-411226-LAC-2 from Santa Cruz Biotechnology
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PP11 siRNA (h) - sc-95700 from Santa Cruz Biotechnology
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PP11 shRNA Plasmid (h) - sc-95700-SH from Santa Cruz Biotechnology
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PP11 shRNA (h) Lentiviral Particles - sc-95700-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU025851 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7867 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7867 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08260 from Sigma-Aldrich
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ENDOU siRNA (Human) - CRH5891 from Cohesion Biosciences
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ENDOU - MBS8213899 from MyBioSource
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shRNA set against Human ENDOU (NM_006025.3) - SHH285753 from Creative biogene
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Human ENDOU siRNA - orb266393 from Biorbyt
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ENDOU shRNA Plasmid (Human) - CHH5891 from Cohesion Biosciences
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ENDOU miRNA 3'UTR clone - MiUTR3H-08672 from Creative biogene
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