| Gene Symbol |
CNTN2
|
| Entrez Gene |
6900
|
| Alt Symbol |
AXT, FAME5, TAG-1, TAX, TAX1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
contactin 2 (axonal)
|
| Other Description |
axonal glycoprotein TAG-1|axonin-1 cell adhesion molecule|contactin 2 (transiently expressed)|contactin-2|transient axonal glycoprotein 1|transiently-expressed axonal glycoprotein
|
| Swissprots |
Q5T054 Q02246 P78432
|
| Accessions |
CAA59137 CAA63365 EAW91533 EAW91534 Q02246 AB074271 AK095531 AK124736 BAG54084 AK289985 BAF82674 AK309108 BC036477 BC129986 AAI29987 CN289415 CR749495 CAH18318 X67734 CAA47963 X68274 CAA48335 XM_011509925 XP_011508227 NM_005076 NP_005067
|
| Function |
In conjunction with another transmembrane protein, CNTNAP2, contributes to the organization of axonal domains at nodes of Ranvier by maintaining voltage-gated potassium channels at the juxtaparanodal region. May be involved in cell adhesion. {ECO:0000269|PubMed:23518707}.
|
| Subcellular Location |
Cell membrane; Lipid-anchor, GPI-anchor. Note=Attached to the neuronal membrane by a GPI-anchor and is also released from neurons.
|
| Top Pathways |
Cell adhesion molecules (CAMs)
|
![Western Blot: Contactin 2 Overexpression Lysate (Adult Normal) [NBP2-10520] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Contactin 2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2157_Contactin%25202%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10520-img0001.jpg)