Gene Symbol | CNTN2 |
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Entrez Gene | 6900 |
Alt Symbol | AXT, FAME5, TAG-1, TAX, TAX1 |
Species | Human |
Gene Type | protein-coding |
Description | contactin 2 (axonal) |
Other Description | axonal glycoprotein TAG-1|axonin-1 cell adhesion molecule|contactin 2 (transiently expressed)|contactin-2|transient axonal glycoprotein 1|transiently-expressed axonal glycoprotein |
Swissprots | Q5T054 Q02246 P78432 |
Accessions | CAA59137 CAA63365 EAW91533 EAW91534 Q02246 AB074271 AK095531 AK124736 BAG54084 AK289985 BAF82674 AK309108 BC036477 BC129986 AAI29987 CN289415 CR749495 CAH18318 X67734 CAA47963 X68274 CAA48335 XM_011509925 XP_011508227 NM_005076 NP_005067 |
Function | In conjunction with another transmembrane protein, CNTNAP2, contributes to the organization of axonal domains at nodes of Ranvier by maintaining voltage-gated potassium channels at the juxtaparanodal region. May be involved in cell adhesion. {ECO:0000269|PubMed:23518707}. |
Subcellular Location | Cell membrane; Lipid-anchor, GPI-anchor. Note=Attached to the neuronal membrane by a GPI-anchor and is also released from neurons. |
Top Pathways | Cell adhesion molecules (CAMs) |
Contactin 2 CRISPR/Cas9 KO Plasmid (h) - sc-406301 from Santa Cruz Biotechnology
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Contactin 2 HDR Plasmid (h) - sc-406301-HDR from Santa Cruz Biotechnology
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Contactin 2 Double Nickase Plasmid (h) - sc-406301-NIC from Santa Cruz Biotechnology
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Contactin 2 Double Nickase Plasmid (h2) - sc-406301-NIC-2 from Santa Cruz Biotechnology
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Contactin 2 CRISPR Activation Plasmid (h) - sc-406301-ACT from Santa Cruz Biotechnology
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Contactin 2 CRISPR Activation Plasmid (h2) - sc-406301-ACT-2 from Santa Cruz Biotechnology
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Contactin 2 Lentiviral Activation Particles (h) - sc-406301-LAC from Santa Cruz Biotechnology
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Contactin 2 Lentiviral Activation Particles (h2) - sc-406301-LAC-2 from Santa Cruz Biotechnology
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Contactin 2 siRNA (h) - sc-43087 from Santa Cruz Biotechnology
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Contactin 2 shRNA Plasmid (h) - sc-43087-SH from Santa Cruz Biotechnology
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Contactin 2 shRNA (h) Lentiviral Particles - sc-43087-V from Santa Cruz Biotechnology
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Contactin-2/TAG1 RNAi - H00006900-R01 from Novus Biologicals
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MISSION® esiRNA - EHU022851 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6341 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6341 from Sigma-Aldrich
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CNTN2 siRNA (Human) - CRH4726 from Cohesion Biosciences
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CNTN2 - MBS8241308 from MyBioSource
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Contactin 2 CRISPR/Cas9 KO Plasmid (h2) - sc-406301-KO-2 from Santa Cruz Biotechnology
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Contactin 2 HDR Plasmid (h2) - sc-406301-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human CNTN2 (NM_005076.3) - SHH266681 from Creative biogene
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Human CNTN2 siRNA - orb265228 from Biorbyt
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CNTN2 shRNA Plasmid (Human) - CHH4726 from Cohesion Biosciences
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CNTN2 miRNA 3'UTR clone - MiUTR4H-TG02242 from Creative biogene
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