| Gene Symbol |
CUZD1
|
| Entrez Gene |
50624
|
| Alt Symbol |
ERG-1, UO-44
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
CUB and zona pellucida-like domains 1
|
| Other Description |
CUB and ZP domain-containing protein 1|CUB and zona pellucida-like domain-containing protein 1|estrogen regulated gene 1|transmembrane protein UO-44
|
| Swissprots |
Q9HAR7 Q86SG1 D3DRE5 Q7Z660 Q86UP5 Q86UP6 A8K080 B2RN93 Q7Z661
|
| Accessions |
EAW49303 Q86UP6 AF305835 AAG23215 AK289445 BAF82134 AY260047 AAP15458 AY260048 AAP15459 AY260049 AAP15460 AY260050 AAP15461 BC136755 AAI36756 BC144398 BX538283 CAD98079 BX538284 CAD98080 BX648572 NM_022034 NP_071317 NR_037912
|
| Function |
CUZD1 antiserum inhibits cell attachment and proliferation of ovarian cancer cells so may be involved in these processes. May also play a role in the uterus during late pregnancy and/or in trypsin activation in pancreatic acinar cells. {ECO:0000250|UniProtKB:P70412, ECO:0000269|PubMed:15184879}.
|
| Subcellular Location |
Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Associated with zymogen granule membranes. {ECO:0000250}.
|
| Tissue Specificity |
Detected in pancreas and epithelium of ovary. Expressed at higher levels in ovarian tumors than in normal tissue. {ECO:0000269|PubMed:15184879}.
|