Gene Symbol | CUZD1 |
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Entrez Gene | 50624 |
Alt Symbol | ERG-1, UO-44 |
Species | Human |
Gene Type | protein-coding |
Description | CUB and zona pellucida-like domains 1 |
Other Description | CUB and ZP domain-containing protein 1|CUB and zona pellucida-like domain-containing protein 1|estrogen regulated gene 1|transmembrane protein UO-44 |
Swissprots | Q9HAR7 Q86SG1 D3DRE5 Q7Z660 Q86UP5 Q86UP6 A8K080 B2RN93 Q7Z661 |
Accessions | EAW49303 Q86UP6 AF305835 AAG23215 AK289445 BAF82134 AY260047 AAP15458 AY260048 AAP15459 AY260049 AAP15460 AY260050 AAP15461 BC136755 AAI36756 BC144398 BX538283 CAD98079 BX538284 CAD98080 BX648572 NM_022034 NP_071317 NR_037912 |
Function | CUZD1 antiserum inhibits cell attachment and proliferation of ovarian cancer cells so may be involved in these processes. May also play a role in the uterus during late pregnancy and/or in trypsin activation in pancreatic acinar cells. {ECO:0000250|UniProtKB:P70412, ECO:0000269|PubMed:15184879}. |
Subcellular Location | Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Associated with zymogen granule membranes. {ECO:0000250}. |
Tissue Specificity | Detected in pancreas and epithelium of ovary. Expressed at higher levels in ovarian tumors than in normal tissue. {ECO:0000269|PubMed:15184879}. |
CUZD1 CRISPR/Cas9 KO Plasmid (h) - sc-407311 from Santa Cruz Biotechnology
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CUZD1 HDR Plasmid (h) - sc-407311-HDR from Santa Cruz Biotechnology
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CUZD1 Double Nickase Plasmid (h) - sc-407311-NIC from Santa Cruz Biotechnology
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CUZD1 Double Nickase Plasmid (h2) - sc-407311-NIC-2 from Santa Cruz Biotechnology
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CUZD1 CRISPR Activation Plasmid (h) - sc-407311-ACT from Santa Cruz Biotechnology
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CUZD1 CRISPR Activation Plasmid (h2) - sc-407311-ACT-2 from Santa Cruz Biotechnology
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CUZD1 Lentiviral Activation Particles (h) - sc-407311-LAC from Santa Cruz Biotechnology
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CUZD1 Lentiviral Activation Particles (h2) - sc-407311-LAC-2 from Santa Cruz Biotechnology
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CUZD1 siRNA (h) - sc-90351 from Santa Cruz Biotechnology
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CUZD1 shRNA Plasmid (h) - sc-90351-SH from Santa Cruz Biotechnology
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CUZD1 shRNA (h) Lentiviral Particles - sc-90351-V from Santa Cruz Biotechnology
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CUZD1 RNAi - H00050624-R02 from Novus Biologicals
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MISSION® esiRNA - EHU093411 from Sigma-Aldrich
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MISSION® esiRNA - EHU088401 from Sigma-Aldrich
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MISSION® esiRNA - EHU116461 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6784 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6784 from Sigma-Aldrich
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CUZD1 siRNA (Human) - CRH9392 from Cohesion Biosciences
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CUZD1 - MBS8218052 from MyBioSource
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CUZD1 CRISPR/Cas9 KO Plasmid (h2) - sc-407311-KO-2 from Santa Cruz Biotechnology
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CUZD1 HDR Plasmid (h2) - sc-407311-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human CUZD1 (NM_022034.5) - SHH271977 from Creative biogene
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CUZD1 shRNA Plasmid (Human) - CHH9392 from Cohesion Biosciences
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CUZD1 miRNA 3'UTR clone - MiUTR3H-14537 from Creative biogene
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