| Gene Symbol |
C9orf89
|
| Entrez Gene |
84270
|
| Alt Symbol |
BinCARD, bA370F5.1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
chromosome 9 open reading frame 89
|
| Other Description |
Bcl10-interacting protein with CARD|bcl10-interacting CARD protein
|
| Swissprots |
Q5BJH8 Q9BSY2 Q96LW7
|
| Accessions |
EAW62850 EAW62851 EAW62852 EAW62853 EAW62854 EAW62855 Q96LW7 AK057716 BAB71550 AK091611 AK097977 AK128259 AW207349 BC004500 AAH04500 BC038856 AAH38856 BC042201 BC091476 XM_005252273 XP_005252330 XM_005252274 XP_005252331 XM_011519093 XP_011517395 XR_929848 NM_032310 NP_115686
|
| Function |
Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner. {ECO:0000269|PubMed:15637807}.
|
| Subcellular Location |
Isoform 1: Nucleus {ECO:0000269|PubMed:23633586}. Note=Coexpression with BCL10 induced translocation from nucleus to cytosol.
|
| Tissue Specificity |
Expressed in ovary, testis, placenta, skeletal muscle, kidney, lung, heart and liver (at protein level). Expressed in thymus and brain. {ECO:0000269|PubMed:15637807}.
|
![Western Blot: bcl10-interacting CARD protein Overexpression Lysate (Adult Normal) [NBL1-08606] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for bcl10-interacting CARD protein.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9090_bcl10-interacting%2520CARD%2520protein%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-08606-img0002.jpg)