Gene Symbol | C9orf89 |
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Entrez Gene | 84270 |
Alt Symbol | BinCARD, bA370F5.1 |
Species | Human |
Gene Type | protein-coding |
Description | chromosome 9 open reading frame 89 |
Other Description | Bcl10-interacting protein with CARD|bcl10-interacting CARD protein |
Swissprots | Q5BJH8 Q9BSY2 Q96LW7 |
Accessions | EAW62850 EAW62851 EAW62852 EAW62853 EAW62854 EAW62855 Q96LW7 AK057716 BAB71550 AK091611 AK097977 AK128259 AW207349 BC004500 AAH04500 BC038856 AAH38856 BC042201 BC091476 XM_005252273 XP_005252330 XM_005252274 XP_005252331 XM_011519093 XP_011517395 XR_929848 NM_032310 NP_115686 |
Function | Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner. {ECO:0000269|PubMed:15637807}. |
Subcellular Location | Isoform 1: Nucleus {ECO:0000269|PubMed:23633586}. Note=Coexpression with BCL10 induced translocation from nucleus to cytosol. |
Tissue Specificity | Expressed in ovary, testis, placenta, skeletal muscle, kidney, lung, heart and liver (at protein level). Expressed in thymus and brain. {ECO:0000269|PubMed:15637807}. |
BinCARD CRISPR/Cas9 KO Plasmid (h) - sc-413602 from Santa Cruz Biotechnology
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BinCARD HDR Plasmid (h) - sc-413602-HDR from Santa Cruz Biotechnology
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BinCARD Double Nickase Plasmid (h) - sc-413602-NIC from Santa Cruz Biotechnology
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BinCARD Double Nickase Plasmid (h2) - sc-413602-NIC-2 from Santa Cruz Biotechnology
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BinCARD CRISPR Activation Plasmid (h) - sc-413602-ACT from Santa Cruz Biotechnology
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BinCARD CRISPR Activation Plasmid (h2) - sc-413602-ACT-2 from Santa Cruz Biotechnology
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BinCARD Lentiviral Activation Particles (h) - sc-413602-LAC from Santa Cruz Biotechnology
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BinCARD Lentiviral Activation Particles (h2) - sc-413602-LAC-2 from Santa Cruz Biotechnology
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BinCARD siRNA (h) - sc-92507 from Santa Cruz Biotechnology
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BinCARD shRNA Plasmid (h) - sc-92507-SH from Santa Cruz Biotechnology
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BinCARD shRNA (h) Lentiviral Particles - sc-92507-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN5233 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5233 from Sigma-Aldrich
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C9orf89 siRNA (Human) - CRJ3396 from Cohesion Biosciences
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C9orf89 - MBS8200392 from MyBioSource
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shRNA set against Human C9orf89 (NM_032310.3) - SHH253009 from Creative biogene
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C9orf89 shRNA Plasmid (Human) - CHJ3396 from Cohesion Biosciences
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C9ORF89 miRNA 3'UTR clone - MiUTR1H-01549 from Creative biogene
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