| Gene Symbol |
TES
|
| Entrez Gene |
26136
|
| Alt Symbol |
TESS, TESS-2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
testin LIM domain protein
|
| Other Description |
testin|testis derived transcript (3 LIM domains)
|
| Swissprots |
Q9HAJ9 Q9UGI8 Q9GZQ1 A4D0U6
|
| Accessions |
AAG17635 AAG17636 AAQ93367 EAL24364 EAL24365 EAW83494 EAW83495 EAW83496 EAW83497 Q9UGI8 AF147329 AF245356 AAG17612 AF245357 AAG17613 AJ250865 CAB65119 AK021575 BAB13846 AK222840 BAD96560 AK291802 BAF84491 AK299104 BAH12951 AK300546 BAH13301 AK309324 AK310995 AK315644 BAG38011 AL050162 CAB43302 BC001451 AAH01451 BC040208 BC045580 DC341259 EU176352 ABW03803 EU176694 ABW03495 GQ423971 ACV74338 XM_005250258 XP_005250315 NM_015641 NP_056456 NM_152829 NP_690042
|
| Function |
Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor. Inhibits tumor cell growth. {ECO:0000269|PubMed:11420696, ECO:0000269|PubMed:12571287, ECO:0000269|PubMed:12695497}.
|
| Subcellular Location |
Cytoplasm. Cell junction, focal adhesion. Note=Detected along actin stress fibers.
|
| Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:11420696}.
|
![Western Blot: Testin Overexpression Lysate (Adult Normal) [NBP2-07137] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Testin.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8482_Testin%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07137-img0001.jpg)