Gene Symbol | TES |
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Entrez Gene | 26136 |
Alt Symbol | TESS, TESS-2 |
Species | Human |
Gene Type | protein-coding |
Description | testin LIM domain protein |
Other Description | testin|testis derived transcript (3 LIM domains) |
Swissprots | Q9HAJ9 Q9UGI8 Q9GZQ1 A4D0U6 |
Accessions | AAG17635 AAG17636 AAQ93367 EAL24364 EAL24365 EAW83494 EAW83495 EAW83496 EAW83497 Q9UGI8 AF147329 AF245356 AAG17612 AF245357 AAG17613 AJ250865 CAB65119 AK021575 BAB13846 AK222840 BAD96560 AK291802 BAF84491 AK299104 BAH12951 AK300546 BAH13301 AK309324 AK310995 AK315644 BAG38011 AL050162 CAB43302 BC001451 AAH01451 BC040208 BC045580 DC341259 EU176352 ABW03803 EU176694 ABW03495 GQ423971 ACV74338 XM_005250258 XP_005250315 NM_015641 NP_056456 NM_152829 NP_690042 |
Function | Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor. Inhibits tumor cell growth. {ECO:0000269|PubMed:11420696, ECO:0000269|PubMed:12571287, ECO:0000269|PubMed:12695497}. |
Subcellular Location | Cytoplasm. Cell junction, focal adhesion. Note=Detected along actin stress fibers. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:11420696}. |
TES CRISPR/Cas9 KO Plasmid (h) - sc-404875 from Santa Cruz Biotechnology
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TES HDR Plasmid (h) - sc-404875-HDR from Santa Cruz Biotechnology
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TES Double Nickase Plasmid (h) - sc-404875-NIC from Santa Cruz Biotechnology
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TES Double Nickase Plasmid (h2) - sc-404875-NIC-2 from Santa Cruz Biotechnology
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TES CRISPR Activation Plasmid (h) - sc-404875-ACT from Santa Cruz Biotechnology
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TES CRISPR Activation Plasmid (h2) - sc-404875-ACT-2 from Santa Cruz Biotechnology
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TES Lentiviral Activation Particles (h) - sc-404875-LAC from Santa Cruz Biotechnology
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TES Lentiviral Activation Particles (h2) - sc-404875-LAC-2 from Santa Cruz Biotechnology
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TES siRNA (h) - sc-45509 from Santa Cruz Biotechnology
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TES shRNA Plasmid (h) - sc-45509-SH from Santa Cruz Biotechnology
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TES shRNA (h) Lentiviral Particles - sc-45509-V from Santa Cruz Biotechnology
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Testin RNAi - H00026136-R01 from Novus Biologicals
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Testin RNAi - H00026136-R02 from Novus Biologicals
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MISSION® esiRNA - EHU133181 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21221 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21221 from Sigma-Aldrich
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TES siRNA (Human) - CRH8726 from Cohesion Biosciences
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TES - MBS8217612 from MyBioSource
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shRNA set against Human TES (NM_015641.3) - SHH425752 from Creative biogene
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Human TES siRNA - orb269228 from Biorbyt
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TES shRNA Plasmid (Human) - CHH8726 from Cohesion Biosciences
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TES miRNA 3'UTR clone - MiUTR3H-08200 from Creative biogene
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TES miRNA 3'UTR clone - MiUTR3H-08201 from Creative biogene
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