Gene Symbol | NFS1 |
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Entrez Gene | 9054 |
Alt Symbol | HUSSY-08, IscS, NIFS |
Species | Human |
Gene Type | protein-coding |
Description | NFS1 cysteine desulfurase |
Other Description | NFS1 nitrogen fixation 1 homolog|cysteine desulfurase, mitochondrial|nitrogen fixation 1 (S. cerevisiae, homolog)|nitrogen-fixing bacteria S-like protein |
Swissprots | F5GYK5 E1P5R8 B4DXK9 B3KMA5 Q9Y481 Q6P0L8 Q9NTZ5 Q9Y697 |
Accessions | CAB87612 EAW76170 EAW76171 EAW76172 Q9Y697 AF097025 AAD09187 AJ010952 CAA09424 AK001265 AK001470 BAG50917 AK056242 BAG51655 AK091049 AK223239 BAD96959 AK295215 BAG58209 AK297969 BAG60279 AK301969 BAG63382 AK302023 BAG63421 AK312293 BAG35220 BC018471 AAH18471 BC065560 AAH65560 DA082829 HQ448113 ADQ32594 JF432612 ADZ15829 R16676 NM_001198989 NP_001185918 NM_021100 NP_066923 NR_037570 NM_181679 |
Function | Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron- sulfur (Fe-S) clusters. May be involved in the biosynthesis of molybdenum cofactor. {ECO:0000269|PubMed:18650437}. |
Subcellular Location | Isoform Mitochondrial: Mitochondrion. |
Tissue Specificity | Predominantly expressed in heart and skeletal muscle. Also found in brain, liver and pancreas. |
Top Pathways | Sulfur relay system, Thiamine metabolism |
NFS1 (B-7) - sc-365308 from Santa Cruz Biotechnology
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NFS1 (L-20) - sc-85786 from Santa Cruz Biotechnology
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NFS1 (H-170) - sc-98420 from Santa Cruz Biotechnology
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NFS1 (A-19) - sc-85784 from Santa Cruz Biotechnology
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NFS1 (C-16) - sc-85785 from Santa Cruz Biotechnology
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NFS1 (2635E1a) - sc-81107 from Santa Cruz Biotechnology
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Anti-NFS1 antibody - ab197253 from Abcam
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Anti-NFS1 antibody - ab172252 from Abcam
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Anti-NFS1 antibody - ab66272 from Abcam
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Anti-NFS1 antibody - ab129596 from Abcam
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Anti-NFS1 antibody [2635E1a] - ab58623 from Abcam
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Anti-NFS1 Antibody - LS-C73516 from LifeSpan Bioscience
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Anti-NFS1 Antibody (clone 2635E1a) - LS-C184569 from LifeSpan Bioscience
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Anti-NFS1 Antibody (aa121-149, AP) - LS-C264325 from LifeSpan Bioscience
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Anti-NFS1 Antibody (aa121-149, APC) - LS-C264326 from LifeSpan Bioscience
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Anti-NFS1 Antibody (aa121-149, Biotin) - LS-C264327 from LifeSpan Bioscience
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Anti-NFS1 Antibody (aa151-200) - LS-C31084 from LifeSpan Bioscience
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Anti-NFS1 Antibody (aa121-149, FITC) - LS-C264328 from LifeSpan Bioscience
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Anti-NFS1 Antibody (aa120-149) - LS-C323324 from LifeSpan Bioscience
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Anti-NFS1 Antibody (aa121-149, PE) - LS-C264334 from LifeSpan Bioscience
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Anti-NFS1 Antibody (aa121-149, Azide-free, HRP) - LS-C264333 from LifeSpan Bioscience
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Anti-NFS1 Antibody (aa121-149) - LS-C164856 from LifeSpan Bioscience
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Anti-NFS1 Antibody - LS-C334863 from LifeSpan Bioscience
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Anti-NFS1 Antibody (aa1-299, clone 5D1) - LS-C339730 from LifeSpan Bioscience
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Anti-NFS1 Antibody (aa1-299, clone 2H5) - LS-C339610 from LifeSpan Bioscience
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