Gene Symbol |
ASIC4
|
Entrez Gene |
55515
|
Alt Symbol |
ACCN4, BNAC4
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
acid sensing (proton gated) ion channel family member 4
|
Other Description |
acid-sensing (proton-gated) ion channel family member 4|acid-sensing ion channel 4|amiloride-sensitive cation channel 4, pituitary|amiloride-sensitive cation channel family member 4, pituitary|brain sodium channel 4
|
Swissprots |
Q6PIN9 Q53SB7 Q9NQA4 Q6GMS1 Q96FT7
|
Accessions |
AAY15054 CAB93980 CAC51338 EAW70760 EAW70761 EAW70762 EAW70763 Q96FT7 AK308804 AK309373 BC010439 AAH10439 BC031812 AAH31812 BC073912 DQ892104 ABM83030 EL736952 XM_005246671 XP_005246728 XM_011511438 XP_011509740 XM_011511439 XP_011509741 XM_011511440 XP_011509742 XM_011511441 XP_011509743 NM_182847 NP_878267 NM_018674
|
Function |
Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity. {ECO:0000269|PubMed:10852210}.
|
Subcellular Location |
Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
Tissue Specificity |
Expressed in pituitary gland. Weakly expressed in brain, vestibular system and organ of Corti. {ECO:0000269|PubMed:10852210}.
|
Top Pathways |
Inflammatory mediator regulation of TRP channels
|