Gene Symbol | ASIC4 |
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Entrez Gene | 55515 |
Alt Symbol | ACCN4, BNAC4 |
Species | Human |
Gene Type | protein-coding |
Description | acid sensing (proton gated) ion channel family member 4 |
Other Description | acid-sensing (proton-gated) ion channel family member 4|acid-sensing ion channel 4|amiloride-sensitive cation channel 4, pituitary|amiloride-sensitive cation channel family member 4, pituitary|brain sodium channel 4 |
Swissprots | Q6PIN9 Q53SB7 Q9NQA4 Q6GMS1 Q96FT7 |
Accessions | AAY15054 CAB93980 CAC51338 EAW70760 EAW70761 EAW70762 EAW70763 Q96FT7 AK308804 AK309373 BC010439 AAH10439 BC031812 AAH31812 BC073912 DQ892104 ABM83030 EL736952 XM_005246671 XP_005246728 XM_011511438 XP_011509740 XM_011511439 XP_011509741 XM_011511440 XP_011509742 XM_011511441 XP_011509743 NM_182847 NP_878267 NM_018674 |
Function | Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity. {ECO:0000269|PubMed:10852210}. |
Subcellular Location | Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Tissue Specificity | Expressed in pituitary gland. Weakly expressed in brain, vestibular system and organ of Corti. {ECO:0000269|PubMed:10852210}. |
Top Pathways | Inflammatory mediator regulation of TRP channels |
ASIC4 CRISPR/Cas9 KO Plasmid (h) - sc-406175 from Santa Cruz Biotechnology
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ASIC4 HDR Plasmid (h) - sc-406175-HDR from Santa Cruz Biotechnology
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ASIC4 Double Nickase Plasmid (h) - sc-406175-NIC from Santa Cruz Biotechnology
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ASIC4 Double Nickase Plasmid (h2) - sc-406175-NIC-2 from Santa Cruz Biotechnology
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ASIC4 CRISPR Activation Plasmid (h) - sc-406175-ACT from Santa Cruz Biotechnology
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ASIC4 CRISPR Activation Plasmid (h2) - sc-406175-ACT-2 from Santa Cruz Biotechnology
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ASIC4 Lentiviral Activation Particles (h) - sc-406175-LAC from Santa Cruz Biotechnology
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ASIC4 Lentiviral Activation Particles (h2) - sc-406175-LAC-2 from Santa Cruz Biotechnology
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ASIC4 siRNA (h) - sc-42411 from Santa Cruz Biotechnology
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ASIC4 shRNA Plasmid (h) - sc-42411-SH from Santa Cruz Biotechnology
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ASIC4 shRNA (h) Lentiviral Particles - sc-42411-V from Santa Cruz Biotechnology
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ACCN4 RNAi - H00055515-R02 from Novus Biologicals
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ACCN4 RNAi - H00055515-R01 from Novus Biologicals
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MISSION® esiRNA - EHU156921 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2710 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2710 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05939 from Sigma-Aldrich
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ASIC4 siRNA (Human) - CRJ0722 from Cohesion Biosciences
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ASIC4 - MBS8212915 from MyBioSource
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shRNA set against Human ACCN4 (NM_182847.2) - SHH230146 from Creative biogene
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Human ASIC4 siRNA - orb271223 from Biorbyt
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ASIC4 shRNA Plasmid (Human) - CHJ0722 from Cohesion Biosciences
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