ACE2

Gene Symbol	ACE2
Entrez Gene	59272
Alt Symbol	ACEH
Species	Human
Gene Type	protein-coding
Description	angiotensin I converting enzyme 2
Other Description	ACE-related carboxypeptidase|angiotensin I converting enzyme (peptidyl-dipeptidase A) 2|angiotensin-converting enzyme 2|angiotensin-converting enzyme homolog|metalloprotease MPROT15|peptidyl-dipeptidase A
Swissprots	Q9NRA7 Q9UFZ6 C7ECU1 Q86WT0 Q6UWP0 Q9BYF1
Accessions	AAO25651 CAC18991 CAD35458 CAD37288 EAW98891 EAW98892 Q9BYF1 AB046569 BAB40370 AB193259 BAD99266 AB193260 BAD99267 AF241254 AAF78220 AF291820 AAF99721 AK026461 AK315144 BAG37592 AL110224 CAB53682 AY358714 AAQ89076 AY623811 AAT45083 BC032938 BC039902 AAH39902 BC048094 AAH48094 BC048144 BC059378 GQ262784 ACT66268 XM_011545549 XP_011543851 XM_011545550 XP_011543852 XM_011545551 XP_011543853 XM_011545552 XP_011543854 NM_021804 NP_068576
Function	Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin- 13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses. {ECO:0000269|PubMed:10924499, ECO:0000269|PubMed:10969042, ECO:0000269|PubMed:14647384, ECO:0000269|PubMed:24227843}.
Subcellular Location	Processed angiotensin-converting enzyme 2: Secreted.
Tissue Specificity	Expressed in endothelial cells from small and large arteries, and in arterial smooth muscle cells. Expressed in lung alveolar epithelial cells, enterocytes of the small intestine, Leydig cells and Sertoli cells (at protein level). Expressed in heart, kidney, testis, and gastrointestinal system. {ECO:0000269|PubMed:10924499, ECO:0000269|PubMed:10969042, ECO:0000269|PubMed:12459472, ECO:0000269|PubMed:15141377, ECO:0000269|PubMed:15231706, ECO:0000269|PubMed:15671045}.
Top Pathways	Protein digestion and absorption, Renin-angiotensin system

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ACE2 / ACE-2 ELISA Kit (Sandwich ELISA) - LS-F2820 from LifeSpan Bioscience Category ELISA Kit Prices $570.00 Sizes 1 plate Sensitivity 10 pg/ml Range 62.5-4000 pg/ml

Mouse ACE2 / ACE-2 ELISA Kit (Sandwich ELISA) - LS-F2871 from LifeSpan Bioscience Category ELISA Kit Prices $570.00 Sizes 1 plate Sensitivity 10 pg/ml Range 62.5-4000 pg/ml

Rat ACE2 / ACE-2 ELISA Kit (Sandwich ELISA) - LS-F5059 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.31 ng/ml Range 62.5-4000 pg/ml

Human ACE2 / ACE-2 ELISA Kit (Sandwich ELISA) - LS-F5886 from LifeSpan Bioscience Category ELISA Kit Prices $460.00 Sizes 1 plate Sensitivity 6.5 pg/ml Range 62.5-4000 pg/ml

Mouse ACE2 / ACE-2 ELISA Kit (Sandwich ELISA) - LS-F7614 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 5.5 pg/ml Range 62.5-4000 pg/ml

Rat ACE2 / ACE-2 ELISA Kit (Sandwich ELISA) - LS-F10723 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 Range 62.5-4000 pg/ml

Human ACE2 / ACE-2 ELISA Kit (Sandwich ELISA) - LS-F10722 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.78 Range 62.5-4000 pg/ml

ACE2 ELISA Kit - 55R-1425 from Fitzgerald Category ELISA Kit Prices $795.00 Sizes 100 assays

Mouse ACE2 ELISA Kit - orb219581 from Biorbyt Category ELISA Kit Prices $706.00 Sizes 96 test Sensitivity 10 pg/ml Range 62.5 pg/ml-4000 pg/ml

Human ACE2 ELISA Kit - abx055274 from Abbexa Category ELISA Kit

Human ACE2 ELISA Kit - abx056001 from Abbexa Category ELISA Kit

Human ACE2 ELISA Kit - abx150520 from Abbexa Category ELISA Kit Sensitivity 6.4 pg/ml Range 15.625 pg/ml - 1000 pg/ml

Angiotensin I Converting Enzyme 2, ACE2, Human, ELISA Kit - E-EL-H0281 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.234 Range 0.391-25ng/mL

Angiotensin converting enzyme 2, ACE2, Human, ELISA Kit - CSB-E04489h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.039 ng/ml Range 0.156 ng/ml-10 ng/ml

Angiotensin I Converting Enzyme 2 (ACE2), Human, ELISA Kit - SEB886Hu from ARP American Research Products Category ELISA Kit Prices $459.00 Sizes 96 t Sensitivity 7.7pg/mL Range 15.6-1,000pg/mL

Angiotensin I Converting Enzyme 2, Human, ELISA Kit - E01A0499 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1 ng/mL Range 1.0-25 ng/mL

Angiotensin-converting enzyme 2, ACE2, Human, ELISA Kit - E1886h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.78-50 ng/mL

Angiotensin I Converting Enzyme 2, ACE2, Rabbit, ELISA Kit - E-EL-RB0996 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Angiotensin I Converting Enzyme 2, ACE2, Chicken, ELISA Kit - E-EL-Ch0950 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Angiotensin I Converting Enzyme 2, ACE2, Porcine, ELISA Kit - E-EL-P0857 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Angiotensin I Converting Enzyme 2, ACE2, Guinea Pig, ELISA Kit - E-EL-GP0563 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Angiotensin I Converting Enzyme 2, ACE2, Monkey, ELISA Kit - E-EL-MK1095 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 46.875 Range 78.125-5000pg/Ml

Human ACE2 ELISA Kit - 68ELH-ACE2 from RayBiotech Category ELISA Kit

Human ACE2 ELISA Kit - HA0506 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine ACE2 ELISA Kit - AA0506 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

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