| Gene Symbol |
MAOB
|
| Entrez Gene |
4129
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
monoamine oxidase B
|
| Other Description |
MAO, brain|MAO, platelet|MAO-B|adrenalin oxidase|amine oxidase [flavin-containing] B|monoamine oxidase type B|tyramine oxidase
|
| Swissprots |
Q7Z6S2 D3DWC3 B7Z5H3 B2R6R3 P27338
|
| Accessions |
AAA59551 AAB46386 EAW59378 EAW59379 EAW59380 P27338 AK294306 BAH11728 AK298942 BAH12909 AK310458 AK312679 BAG35560 AL133791 AU127841 BC022494 AAH22494 BM726427 CA975968 DC326844 GQ129432 ACT64566 GQ129433 ACT64567 M69177 AAA59550 S62734 AAB27229 XM_005272607 XP_005272664 XM_005272608 XP_005272665 XM_011543914 XP_011542216 NM_000898 NP_000889
|
| Function |
Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.
|
| Subcellular Location |
Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side.
|
| Top Pathways |
Glycine, serine and threonine metabolism, Dopaminergic synapse, Amphetamine addiction, Cocaine addiction, Alcoholism
|