Gene Symbol | MAOB |
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Entrez Gene | 4129 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | monoamine oxidase B |
Other Description | MAO, brain|MAO, platelet|MAO-B|adrenalin oxidase|amine oxidase [flavin-containing] B|monoamine oxidase type B|tyramine oxidase |
Swissprots | Q7Z6S2 D3DWC3 B7Z5H3 B2R6R3 P27338 |
Accessions | AAA59551 AAB46386 EAW59378 EAW59379 EAW59380 P27338 AK294306 BAH11728 AK298942 BAH12909 AK310458 AK312679 BAG35560 AL133791 AU127841 BC022494 AAH22494 BM726427 CA975968 DC326844 GQ129432 ACT64566 GQ129433 ACT64567 M69177 AAA59550 S62734 AAB27229 XM_005272607 XP_005272664 XM_005272608 XP_005272665 XM_011543914 XP_011542216 NM_000898 NP_000889 |
Function | Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine. |
Subcellular Location | Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side. |
Top Pathways | Glycine, serine and threonine metabolism, Dopaminergic synapse, Amphetamine addiction, Cocaine addiction, Alcoholism |
MAO-B CRISPR/Cas9 KO Plasmid (h) - sc-401732 from Santa Cruz Biotechnology
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MAO-B HDR Plasmid (h) - sc-401732-HDR from Santa Cruz Biotechnology
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MAO-B Double Nickase Plasmid (h) - sc-401732-NIC from Santa Cruz Biotechnology
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MAO-B Double Nickase Plasmid (h2) - sc-401732-NIC-2 from Santa Cruz Biotechnology
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MAO-B CRISPR Activation Plasmid (h) - sc-401732-ACT from Santa Cruz Biotechnology
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MAO-B CRISPR Activation Plasmid (h2) - sc-401732-ACT-2 from Santa Cruz Biotechnology
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MAO-B Lentiviral Activation Particles (h) - sc-401732-LAC from Santa Cruz Biotechnology
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MAO-B Lentiviral Activation Particles (h2) - sc-401732-LAC-2 from Santa Cruz Biotechnology
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MAO-B siRNA (h) - sc-35849 from Santa Cruz Biotechnology
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MAO-B shRNA Plasmid (h) - sc-35849-SH from Santa Cruz Biotechnology
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MAO-B shRNA (h) Lentiviral Particles - sc-35849-V from Santa Cruz Biotechnology
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Monoamine Oxidase B RNAi - H00004129-R01 from Novus Biologicals
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MISSION® esiRNA - EHU026891 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1840 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1840 from Sigma-Aldrich
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MAOB siRNA (Human) - CRH2805 from Cohesion Biosciences
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shRNA set against Human MAOB (NM_000898.4) - SHH337443 from Creative biogene
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shRNA set against Human MAOB(NM_000898.4) - SHH172955 from Creative biogene
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Human MAOB siRNA - orb263307 from Biorbyt
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MAOB shRNA Plasmid (Human) - CHH2805 from Cohesion Biosciences
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MAOB miRNA 3'UTR clone - MiUTR1H-06044 from Creative biogene
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