Gene Symbol |
GABRR2
|
Entrez Gene |
2570
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
gamma-aminobutyric acid (GABA) A receptor, rho 2
|
Other Description |
GABA-C receptor, rho-2 subunit|gamma-aminobutyric acid receptor subunit rho-2
|
Swissprots |
Q9H153 A2BDE4 P28476
|
Accessions |
EAW48557 P28476 AK293751 BAG57173 BC130352 AAI30353 BC130354 AAI30355 BX490975 DA863180 M86868 AAA52510 XM_011535713 XP_011534015 XM_011535714 XP_011534016 XM_011535715 XP_011534017 XM_011535716 XP_011534018 XM_011535717 XP_011534019 XM_011535718 XP_011534020 NM_002043 NP_002034
|
Function |
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-2 GABA receptor could play a role in retinal neurotransmission.
|
Subcellular Location |
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
|
Top Pathways |
GABAergic synapse, Morphine addiction, Nicotine addiction, Retrograde endocannabinoid signaling, Neuroactive ligand-receptor interaction
|