| Gene Symbol |
APBA3
|
| Entrez Gene |
9546
|
| Alt Symbol |
MGC:15815, X11L2, mint3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
amyloid beta (A4) precursor protein-binding, family A, member 3
|
| Other Description |
X11-like 2 protein|adapter protein X11gamma|amyloid beta (A4) precursor protein-binding, family A, member 3 (X11-like 2)|amyloid beta A4 precursor protein-binding family A member 3|mint-3|neuron-specific X11L2 protein|neuronal munc18-1-interacting protein 3|phosphotyrosine-binding/-interacting domain (PTB)-bearing protein
|
| Swissprots |
Q9UPZ2 O96018 O60483
|
| Accessions |
AAC72275 BAA83094 BAA83517 EAW69290 EAW69291 O96018 AB021638 BAA74430 AB209603 BAD92840 AF029110 AAC17979 BC008338 BC086306 AAH86306 BG938716 BI910038 BM977984 BQ707748 XM_006722950 XP_006723013 XM_006722951 XP_006723014 NM_004886 NP_004877
|
| Function |
May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP. May enhance the activity of HIF1A in macrophages by inhibiting the activity of HIF1AN. {ECO:0000269|PubMed:19726677}.
|
| Subcellular Location |
Cytoplasm, perinuclear region {ECO:0000269|PubMed:19726677}.
|
| Tissue Specificity |
Expressed in all tissues examined with lower levels in brain and testis.
|