Gene Symbol |
RASL11A
|
Entrez Gene |
387496
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
RAS-like, family 11, member A
|
Other Description |
ras-like protein family member 11A
|
Swissprots |
B2RN97 Q6T310
|
Accessions |
EAX08402 Q6T310 AY439004 AAS07577 BC132703 AAI32704 BC136761 AAI36762 HQ258126 ADR82880 XM_005266370 XP_005266427 XM_005266371 XP_005266428 NM_206827 NP_996563
|
Function |
Regulator of rDNA transcription. Acts in cooperation UBF/UBTF and positively regulates RNA polymerase I transcription (By similarity). {ECO:0000250}.
|
Subcellular Location |
Nucleus, nucleolus {ECO:0000250}. Note=Associates with rDNA transcription unit throughout the cell cycle. {ECO:0000250}.
|
Tissue Specificity |
Widely expressed. Down-regulated in prostate tumors compared to normal prostate tissue. High levels found in colon tumor and normal colon tissue followed by small intestine, liver, jejunum, ileum, bladder and aorta. Lowest levels observed in endothelial cells. {ECO:0000269|PubMed:15033445, ECO:0000269|PubMed:17628721}.
|