Gene Symbol | RASL11A |
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Entrez Gene | 387496 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | RAS-like, family 11, member A |
Other Description | ras-like protein family member 11A |
Swissprots | B2RN97 Q6T310 |
Accessions | EAX08402 Q6T310 AY439004 AAS07577 BC132703 AAI32704 BC136761 AAI36762 HQ258126 ADR82880 XM_005266370 XP_005266427 XM_005266371 XP_005266428 NM_206827 NP_996563 |
Function | Regulator of rDNA transcription. Acts in cooperation UBF/UBTF and positively regulates RNA polymerase I transcription (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus, nucleolus {ECO:0000250}. Note=Associates with rDNA transcription unit throughout the cell cycle. {ECO:0000250}. |
Tissue Specificity | Widely expressed. Down-regulated in prostate tumors compared to normal prostate tissue. High levels found in colon tumor and normal colon tissue followed by small intestine, liver, jejunum, ileum, bladder and aorta. Lowest levels observed in endothelial cells. {ECO:0000269|PubMed:15033445, ECO:0000269|PubMed:17628721}. |
RASL11A CRISPR/Cas9 KO Plasmid (h) - sc-409106 from Santa Cruz Biotechnology
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RASL11A HDR Plasmid (h) - sc-409106-HDR from Santa Cruz Biotechnology
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RASL11A Double Nickase Plasmid (h) - sc-409106-NIC from Santa Cruz Biotechnology
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RASL11A Double Nickase Plasmid (h2) - sc-409106-NIC-2 from Santa Cruz Biotechnology
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RASL11A CRISPR Activation Plasmid (h) - sc-409106-ACT from Santa Cruz Biotechnology
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RASL11A CRISPR Activation Plasmid (h2) - sc-409106-ACT-2 from Santa Cruz Biotechnology
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RASL11A Lentiviral Activation Particles (h) - sc-409106-LAC from Santa Cruz Biotechnology
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RASL11A Lentiviral Activation Particles (h2) - sc-409106-LAC-2 from Santa Cruz Biotechnology
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RASL11A siRNA (h) - sc-106483 from Santa Cruz Biotechnology
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RASL11A shRNA Plasmid (h) - sc-106483-SH from Santa Cruz Biotechnology
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RASL11A shRNA (h) Lentiviral Particles - sc-106483-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU008231 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17991 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17991 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00980 from Sigma-Aldrich
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RASL11A siRNA (Human) - CRJ7738 from Cohesion Biosciences
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RASL11A - MBS8229516 from MyBioSource
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shRNA set against Human RASL11A (NM_206827.1) - SHH390108 from Creative biogene
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shRNA set against Human RASL11A(NM_206827.1) - SHR166746 from Creative biogene
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Human RASL11A siRNA - orb278239 from Biorbyt
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RASL11A shRNA Plasmid (Human) - CHJ7738 from Cohesion Biosciences
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RASL11A miRNA 3'UTR clone - MiUTR1H-08649 from Creative biogene
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