ACTL6B

Gene Symbol	ACTL6B
Entrez Gene	51412
Alt Symbol	ACTL6, BAF53B
Species	Human
Gene Type	protein-coding
Description	actin-like 6B
Other Description	53 kDa BRG1-associated factor B|BRG1-associated factor 53B|actin-like 6|actin-like protein 6B|actin-related protein Baf53b|arpNalpha|hArpN alpha
Swissprots	O75421 O94805 A4D2D0
Accessions	AAP21874 EAL23823 EAW76502 EAW76503 EAW76504 EAW76505 O94805 AB015906 BAA74576 AF041475 AAD54678 AK314940 BAG37446 BC008582 BC020944 AAH20944 BM696009 HQ447891 ADQ32375 XR_927476 NM_016188 NP_057272
Function	Belongs to the chromatin remodeling brain-specific BAF (bBAF) complex, as such plays a role in remodeling mononucleosomes in an ATP-dependent fashion. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex) and is required for postmitotic neural development and dendritic outgrowth. During neural development a switch from a stem/progenitor to a post- mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multi
Subcellular Location	Nucleus.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

BAF53B / ACTL6B Antibody Blocking Peptide - LS-E7814 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BAF53B / ACTL6B Antibody Blocking Peptide - LS-E20702 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ACTL6B-Antibody-N-term-Blocking-peptide - BP5327a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ACTL6B Blocking Peptide - 33R-3319 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

BAF53A Peptide - AC21-0541-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

BAF53A Peptide - 45-314P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

Recombinant Human ACTL6B, His-tagged - ACTL6B-26300TH from Creative Biomart Category Protein Source E. coli

Recombinant Human Actin-like protein 6B(ACTL6B) - CSB-YP001237HU CSB-EP001237HU CSB-BP001237HU CSB-MP001237HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Actin-like protein 6B(ACTL6B) - MBS1160525 from MyBioSource Category Protein Prices $1,940.00, $1,940.00, $2,405.00, $2,405.00 Sizes 1 mg (E Coli Derived), 100 µg (Baculovirus Derived), 1 mg (Yeast Derived), 100 µg (Mammalian Cell Derived) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

ACTL6B Recombinant Protein Antigen - NBP1-91648PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ACTL6B Peptide, Human - M34GP00192H from Creative Peptides Category Peptide Source Synthetic. Species Human

ACTL6B fusion protein - Ag25745 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

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