ADGRL2

Gene Symbol ADGRL2
Entrez Gene 23266
Alt Symbol CIRL2, CL2, LEC1, LPHH1, LPHN2
Species Human
Gene Type protein-coding
Description adhesion G protein-coupled receptor L2
Other Description calcium-independent alpha-latrotoxin receptor 2|latrophilin 2|latrophilin homolog 1|latrophilin-2|lectomedin-1
Swissprots B1ALU5 B1ALU4 Q9UKY6 Q9UKY5 B1ALU2 B1ALT9 B1ALU0 B1ALU6 B1ALT8 Q5VX76 O94882 O95490 A5XEI2
Accessions CAB60201 CAB60202 CAB60203 CAB60204 CAB60205 CAB60206 CAB60207 CAB60229 EAX06321 EAX06322 EAX06323 EAX06324 EAX06325 EAX06326 EAX06327 EAX06328 EAX06329 EAX06330 EAX06331 EAX06332 EAX06333 EAX06334 EAX06335 EAX06336 EAX06337 EAX06338 EAX06339 EAX06340 EAX06341 O95490 AB018329 BAA34506 AF104266 AAD54675 AF104938 AAD54676 AF104939 AAD54677 AJ131581 CAA10458 AK123422 BAG53903 AW008295 BC031321 BM983870 DQ925675 ABL59902 XM_005270666 XP_005270723 XM_005270667 XP_005270724 XM_005270668 XP_005270725 XM_005270670 XP_005270727 XM_005270673 XP_005270730 XM_006710485 XP_006710548 XM_006710488 XP_006710551 XM_006710489 XP_006710552 XM_006710490 XP_006710553 XM_006710491 XP_006710554 XM_006710493 XP_006710556 XM_006710494 XP_006710557 XM_006710497 XP_006710560 XM_011541093 XP_011539395 XM_011541094 XP_011539396 XM_011541095 XP_011539397 XM_011541096 XP_011539398 XR_946591 XR_946592 NM_001297704 NP_001284633 NM_001297705 NP_001284634 NM_001297706 NP_001284635 NM_012302 NP_036434
Function Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor propably implicated in the regulation of exocytosis (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Expressed very widely in all normal tissues tested. Expression is variable in tumor cell lines, apparently elevated in some lines and absent or markedly reduced in others. {ECO:0000269|PubMed:10030676}.

Latrophilin-2 (E-3) - sc-514197 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Latrophilin-2 (E-3): sc-514197. Western blot analysis of Latrophilin-2 expression in HISM whole cell lysate.

Latrophilin-2 (A-14) - sc-47091 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Latrophilin-2 (E-20) - sc-47093 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Latrophilin-2 (H-45) - sc-135155 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Latrophilin-2 (H-45): sc-135155. Western blot analysis of Latrophilin-2 expression in human smooth muscle tissue extract.

Latrophilin-2 (T-17) - sc-47094 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-LPHN2 antibody - ab101833 from Abcam

Host Rabbit
Clonality Polyclonal
ICC/IF image of ab101833 stained SKNSH cells. The cells were 100% methanol fixed (5 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab101833, 5µg/ml) overnight at +4°C. The secondary antibody (green) was ab96899, DyLight® 488 goat anti-rabbit IgG(H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-LPHN2 antibody - ab139498 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of COS7 cells, labeling LPHN2, using ab139498 at a 1/100 dilution. The picture on the right is treated with the synthesized peptide.

Anti-ADGRL2 / LPHN2 Antibody (aa551-600) IHC-plus™ - LS-B7725 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-Latrophilin-2 / LPHN2 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7725 dilution 10 ug/ml.

Anti-ADGRL2 / LPHN2 Antibody (N-Terminus) IHC-plus™ - LS-A1133 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-LPHN2 antibody LS-A1133 IHC of human ovary, Graafian follicle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-ADGRL2 / LPHN2 Antibody (N-Terminus) IHC-plus™ - LS-A1132 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-LPHN2 / Latrophilin-2 antibody IHC of human prostate, smooth muscle, benign prostatic hyperplasia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-ADGRL2 / LPHN2 Antibody (C-Terminus) IHC-plus™ - LS-A1136 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-LPHN2 / Latrophilin-2 antibody IHC of human prostate, carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

NUP62 Antibody - NBP1-85091 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NUP62 Antibody [NBP1-85091] - Lane 1: Marker [kDa] 220, 112, 84, 47, 32, 26, 17. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

Latrophilin 2/LPHN2 Antibody - NBP1-82961 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: Latrophilin 2/LPHN2 Antibody [NBP1-82961] - Immunohistochemical staining of human smooth muscle shows strong cytoplasmic positivity in smooth muscle cells.

Latrophilin 2/LPHN2 Antibody - NLS1133 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: Latrophilin 2/LPHN2 Antibody [NLS1133] - Analysis of anti-LPHN2 antibody with human ovary, graafian follicle.

Latrophilin 2/LPHN2 Antibody - NLS1136 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: Latrophilin 2/LPHN2 Antibody [NLS1136] - Anti-LPHN2 / Latrophilin-2 antibody IHC of human prostate, smooth muscle, benign prostatic hyperplasia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Latrophilin 2/LPHN2 Antibody - NLS1132 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: Latrophilin 2/LPHN2 Antibody [NLS1132] - Anti-LPHN2 / Latrophilin-2 antibody IHC of human prostate, smooth muscle, benign prostatic hyperplasia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-LPHN2 antibody produced in rabbit - SAB4500967 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-LPHN2: <B>Cat. No. SAB4500967</B>: Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using Anti-LPHN2 antibody. Cells on the left were treated with the Anti-LPHN2 antibody. Cells on the right (negative control) were treated with both Anti-LPHN2 antibody and the synthesized immunogen peptide.

Anti-LPHN2 antibody produced in rabbit - SAB2900420 from Sigma-Aldrich

Prices $465.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-LPHN2 (C-Terminus), antibody produced in rabbit: <B>Cat. No. SAB2900420</B>: Anti-LPHN2 antibody IHC staining of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-LPHN2 antibody produced in rabbit - HPA013573 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-LPHN2: <B>Cat. No. HPA013573</B>: Immunohistochemical staining of human smooth muscle shows strong cytoplasmic positivity in smooth muscle cells.

Latrophilin 2 antibody [C3], C-term - GTX108244 from GeneTex

Prices $149.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal

Latrophilin 2 antibody - GTX70739 from GeneTex

Prices $319.00
Sizes 25 μg
Host Rabbit
Clonality Polyclonal
Anti-Latrophilin-2 antibody used in Immunohistochemistry. GTX70739

Latrophilin 2 antibody - GTX70741 from GeneTex

Prices $319.00
Sizes 25 μg
Host Rabbit
Clonality Polyclonal
Anti-Latrophilin-2 antibody used in Immunohistochemistry. GTX70741

Latrophilin 2 antibody - GTX71125 from GeneTex

Prices $319.00
Sizes 25 μg
Host Rabbit
Clonality Polyclonal
Anti-Latrophilin-2 antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX71125

LPHN2 Antibody (OAAF04977) - OAAF04977 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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