Gene Symbol | C5 |
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Entrez Gene | 727 |
Alt Symbol | C5D, C5a, C5b, CPAMD4, ECLZB |
Species | Human |
Gene Type | protein-coding |
Description | complement component 5 |
Other Description | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4|C5a anaphylatoxin|anaphylatoxin C5a analog|complement C5|prepro-C5 |
Swissprots | Q27I61 P01031 Q14CJ0 |
Accessions | AAP13242 ABD48959 BAO02074 EAW87480 P01031 AB209031 BAD92268 AK310774 AK310780 AV682721 BC022299 BC113738 AAI13739 BC113740 AAI13741 BG533927 CB250401 M57729 AAA51925 M65134 AAA51856 S79279 AAB35171 T82068 XM_011518980 XP_011517282 XM_011518981 XP_011517283 XM_011518982 XP_011517284 NM_001735 NP_001726 |
Function | Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled. |
Subcellular Location | Secreted. |
Top Pathways | Complement and coagulation cascades, Systemic lupus erythematosus, Prion diseases, Staphylococcus aureus infection, Pertussis |
C5 overexpression lysate - LY419776 from Acris Antibodies
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C5 293 Cell Lysate - 409264 from ABBIOTEC
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C5 Over-expression Lysate Product - GWB-611C50 from Genway Biotech
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Human Complement C5 Deficient Plasma (EDTA) - D510104 from AssayPro
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Human Complement C5 Deficient Plasma (EDTA) - D510105 from AssayPro
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Human Complement C5 Deficient Plasma (EDTA) - D510106 from AssayPro
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Human Complement C5 Deficient Plasma (Heparin) - D510107 from AssayPro
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Human Complement C5 Deficient Plasma (Heparin) - D510108 from AssayPro
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Human Complement C5 Deficient Plasma (Heparin) - D510109 from AssayPro
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Human Complement C5 Deficient Plasma (Sodium Citrate) - D510101 from AssayPro
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Human Complement C5 Deficient Plasma (Sodium Citrate) - D510102 from AssayPro
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Human Complement C5 Deficient Plasma (Sodium Citrate) - D510103 from AssayPro
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Human Complement C5 Deficient Serum - D510110 from AssayPro
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Human Complement C5 Deficient Serum - D510111 from AssayPro
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Human Complement C5 Deficient Serum - D510112 from AssayPro
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Complement C5 Overexpression Lysate (Native) - NBP2-10765 from Novus Biologicals
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Panoply™ Human C5 Knockdown Stable Cell Line - CSC-DC002068 from Creative biogene
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