Gene Symbol | DSN1 |
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Entrez Gene | 79980 |
Alt Symbol | C20orf172, KNL3, MIS13, dJ469A13.2, hKNL-3 |
Species | Human |
Gene Type | protein-coding |
Description | DSN1, MIS12 kinetochore complex component |
Other Description | DSN1, MIND kinetochore complex component, homolog|kinetochore null 3 homolog|kinetochore-associated protein DSN1 homolog |
Swissprots | Q9H8P4 Q5JW55 Q5JW56 B4DWT2 E1P5U9 Q9H410 |
Accessions | EAW76101 EAW76102 EAW76103 EAW76104 EAW76105 EAW76106 EAW76107 EAW76108 Q9H410 AA534892 AK023408 BAB14564 AK093031 BAC04024 AK290738 BAF83427 AK301671 BAG63144 AK301840 BAG63283 BC026011 AAH26011 BC035821 BC058899 AAH58899 HQ448110 ADQ32591 XM_006723876 XP_006723939 NM_001145315 NP_001138787 NM_001145316 NP_001138788 NM_001145317 NP_001138789 NM_001145318 NP_001138790 NM_024918 NP_079194 |
Function | Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. {ECO:0000269|PubMed:15502821, ECO:0000269|PubMed:16585270}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:15502821, ECO:0000269|PubMed:16585270}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:15502821, ECO:0000269|PubMed:16585270}. Note=Associated with the kinetochore. {ECO:0000269|PubMed:15502821, ECO:0000269|PubMed:16585270}. |
DSN1 CRISPR/Cas9 KO Plasmid (h) - sc-408048 from Santa Cruz Biotechnology
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DSN1 HDR Plasmid (h) - sc-408048-HDR from Santa Cruz Biotechnology
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DSN1 Double Nickase Plasmid (h) - sc-408048-NIC from Santa Cruz Biotechnology
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DSN1 Double Nickase Plasmid (h2) - sc-408048-NIC-2 from Santa Cruz Biotechnology
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DSN1 CRISPR Activation Plasmid (h) - sc-408048-ACT from Santa Cruz Biotechnology
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DSN1 CRISPR Activation Plasmid (h2) - sc-408048-ACT-2 from Santa Cruz Biotechnology
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DSN1 Lentiviral Activation Particles (h) - sc-408048-LAC from Santa Cruz Biotechnology
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DSN1 Lentiviral Activation Particles (h2) - sc-408048-LAC-2 from Santa Cruz Biotechnology
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DSN1 siRNA (h) - sc-77188 from Santa Cruz Biotechnology
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DSN1 shRNA Plasmid (h) - sc-77188-SH from Santa Cruz Biotechnology
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DSN1 shRNA (h) Lentiviral Particles - sc-77188-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU018111 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7512 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7512 from Sigma-Aldrich
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DSN1 siRNA (Human) - CRJ2705 from Cohesion Biosciences
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DSN1 - MBS8228168 from MyBioSource
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shRNA set against Human DSN1 (NM_024918.3) - SHH281313 from Creative biogene
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Human DSN1 siRNA - orb273206 from Biorbyt
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DSN1 shRNA Plasmid (Human) - CHJ2705 from Cohesion Biosciences
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DSN1 miRNA 3'UTR clone - MiUTR3H-10449 from Creative biogene
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DSN1 miRNA 3'UTR clone - MiUTR3H-10450 from Creative biogene
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DSN1 miRNA 3'UTR clone - MiUTR3H-10451 from Creative biogene
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DSN1 miRNA 3'UTR clone - MiUTR3H-10452 from Creative biogene
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DSN1 miRNA 3'UTR clone - MiUTR3H-10453 from Creative biogene
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