| Gene Symbol |
TNNC1
|
| Entrez Gene |
7134
|
| Alt Symbol |
CMD1Z, CMH13, TN-C, TNC, TNNC
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
troponin C type 1 (slow)
|
| Other Description |
cardiac troponin C|slow twitch skeletal/cardiac muscle troponin C|troponin C, slow skeletal and cardiac muscles|troponin C1, slow
|
| Swissprots |
P63316
|
| Accessions |
AAA36772 ADL14491 EAW65226 EAW65227 P63316 AF020769 AAB91994 AJ574625 AK313743 BAG36483 BC030244 AAH30244 CR541865 CAG46663 CR541885 CAG46683 DQ891026 ABM81952 DQ894206 ABM85132 X07897 CAA30736 NM_003280 NP_003271
|
| Function |
Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.
|
| Top Pathways |
Calcium signaling pathway, Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Dilated cardiomyopathy, Adrenergic signaling in cardiomyocytes
|
![Western Blot: Troponin C (cardiac) Overexpression Lysate (Adult Normal) [NBL1-17176] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Troponin C (cardiac).](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4434_Troponin%2520C%2520(cardiac)%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17176-img0002.jpg)