Gene Symbol | SMNDC1 |
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Entrez Gene | 10285 |
Alt Symbol | SMNR, SPF30, TDRD16C |
Species | Human |
Gene Type | protein-coding |
Description | survival motor neuron domain containing 1 |
Other Description | 30 kDa splicing factor SMNrp|SMN-related protein|splicing factor 30, survival of motor neuron-related|survival motor neuron domain-containing protein 1|survival of motor neuron-related-splicing factor 30|tudor domain containing 16C |
Swissprots | Q5T3K6 O75940 D3DRB1 B2RA27 |
Accessions | EAW49561 EAW49562 EAW49563 EAW49564 O75940 AF083385 AAC64086 AF107463 AAC84148 AK314013 BAG36724 BC011234 AAH11234 BC039110 BQ694303 XM_005269382 XP_005269439 NM_005871 NP_005862 |
Function | Necessary for spliceosome assembly. Overexpression causes apoptosis. {ECO:0000269|PubMed:11331295, ECO:0000269|PubMed:11331595, ECO:0000269|PubMed:9817934}. |
Subcellular Location | Nucleus speckle. Nucleus, Cajal body. Note=Detected in nuclear speckles containing snRNP and in Cajal (coiled) bodies. |
Tissue Specificity | Detected at intermediate levels in skeletal muscle, and at low levels in heart and pancreas. {ECO:0000269|PubMed:9817934}. |
Top Pathways | Spliceosome |
SPF30 (E-5) - sc-398258 from Santa Cruz Biotechnology
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SPF30 (D-11) - sc-398259 from Santa Cruz Biotechnology
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SPF30 (G-8) - sc-376887 from Santa Cruz Biotechnology
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SPF30 (S-18) - sc-66647 from Santa Cruz Biotechnology
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SPF30 (C-19) - sc-66645 from Santa Cruz Biotechnology
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SPF30 (H-152) - sc-366016 from Santa Cruz Biotechnology
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SPF30 (SQ-16) - sc-100338 from Santa Cruz Biotechnology
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Anti-SMNDC1 antibody - ab89131 from Abcam
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Anti-SMNDC1 antibody - ab56693 from Abcam
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Anti-SMNDC1 antibody - ab155021 from Abcam
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Anti-SMNDC1 Antibody (aa11-41, APC) - LS-C241009 from LifeSpan Bioscience
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Anti-SMNDC1 Antibody (aa11-41, AP) - LS-C241008 from LifeSpan Bioscience
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Anti-SMNDC1 Antibody (aa11-41, Biotin) - LS-C241010 from LifeSpan Bioscience
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Anti-SMNDC1 Antibody (aa11-41, FITC) - LS-C241011 from LifeSpan Bioscience
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Anti-SMNDC1 Antibody (aa11-41, PE) - LS-C241013 from LifeSpan Bioscience
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Anti-SMNDC1 Antibody (C-Terminus) - LS-C101860 from LifeSpan Bioscience
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Anti-SMNDC1 Antibody (aa11-41, Azide-free, HRP) - LS-C248203 from LifeSpan Bioscience
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Anti-SMNDC1 Antibody (C-Terminus) - LS-C80354 from LifeSpan Bioscience
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Anti-SMNDC1 Antibody (aa188-238) - LS-C289548 from LifeSpan Bioscience
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Anti-SMNDC1 Antibody (aa19-48) - LS-C325207 from LifeSpan Bioscience
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Anti-SMNDC1 Antibody (aa100-150) - LS-C289549 from LifeSpan Bioscience
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Anti-SMNDC1 Antibody (aa1-239, Azide-free) - LS-C328808 from LifeSpan Bioscience
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Anti-SMNDC1 Antibody - LS-C192251 from LifeSpan Bioscience
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Anti-SMNDC1 Antibody (clone 2B9) - LS-C133636 from LifeSpan Bioscience
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Anti-SMNDC1 Antibody (aa11-41) - LS-C161316 from LifeSpan Bioscience
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