| Gene Symbol |
SLC22A9
|
| Entrez Gene |
114571
|
| Alt Symbol |
HOAT4, OAT4, OAT7, UST3H, ust3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 22 (organic anion transporter), member 9
|
| Other Description |
organic anion transporter 4|organic anion transporter 7|solute carrier family 22 (organic anion/cation transporter), member 9|solute carrier family 22 member 9
|
| Swissprots |
A0AVB7 Q8IVM8 Q8TEC0 Q8WYN7 Q8TCC8 A4PB24
|
| Accessions |
EAW74146 EAW74147 EAW74148 Q8IVM8 AB062418 BAB83517 AB074812 BAF51552 AF440402 AAP97316 AJ295270 CAC82910 AK074246 BAB85030 BC022379 AAH22379 BC126288 AAI26289 HQ258285 ADR83039 NM_080866 NP_543142
|
| Function |
Sodium-independent organic anion transporter which exhibits high specificity for sulfated conjugates of xenobiotics and steroid hormones. It is also specifically activated by 3 to 5 carbons-containing short-chain fatty acids/SCFAs, including propionate, butyrate and valerate. May operate the exchange of sulfated organic components against short-chain fatty acids/SCFAs at the sinusoidal membrane of hepatocytes. {ECO:0000269|PubMed:17393504}.
|
| Subcellular Location |
Basolateral cell membrane {ECO:0000269|PubMed:17393504}; Multi-pass membrane protein {ECO:0000269|PubMed:17393504}. Note=Enriched at the sinusoidal part of the plasma membrane.
|
| Tissue Specificity |
Specifically expressed in liver by hepatocytes (at protein level). {ECO:0000269|PubMed:11327718, ECO:0000269|PubMed:17393504}.
|