Gene Symbol | SLC22A9 |
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Entrez Gene | 114571 |
Alt Symbol | HOAT4, OAT4, OAT7, UST3H, ust3 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 22 (organic anion transporter), member 9 |
Other Description | organic anion transporter 4|organic anion transporter 7|solute carrier family 22 (organic anion/cation transporter), member 9|solute carrier family 22 member 9 |
Swissprots | A0AVB7 Q8IVM8 Q8TEC0 Q8WYN7 Q8TCC8 A4PB24 |
Accessions | EAW74146 EAW74147 EAW74148 Q8IVM8 AB062418 BAB83517 AB074812 BAF51552 AF440402 AAP97316 AJ295270 CAC82910 AK074246 BAB85030 BC022379 AAH22379 BC126288 AAI26289 HQ258285 ADR83039 NM_080866 NP_543142 |
Function | Sodium-independent organic anion transporter which exhibits high specificity for sulfated conjugates of xenobiotics and steroid hormones. It is also specifically activated by 3 to 5 carbons-containing short-chain fatty acids/SCFAs, including propionate, butyrate and valerate. May operate the exchange of sulfated organic components against short-chain fatty acids/SCFAs at the sinusoidal membrane of hepatocytes. {ECO:0000269|PubMed:17393504}. |
Subcellular Location | Basolateral cell membrane {ECO:0000269|PubMed:17393504}; Multi-pass membrane protein {ECO:0000269|PubMed:17393504}. Note=Enriched at the sinusoidal part of the plasma membrane. |
Tissue Specificity | Specifically expressed in liver by hepatocytes (at protein level). {ECO:0000269|PubMed:11327718, ECO:0000269|PubMed:17393504}. |
SLC22A9 CRISPR/Cas9 KO Plasmid (h) - sc-410252 from Santa Cruz Biotechnology
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SLC22A9 HDR Plasmid (h) - sc-410252-HDR from Santa Cruz Biotechnology
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SLC22A9 Double Nickase Plasmid (h) - sc-410252-NIC from Santa Cruz Biotechnology
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SLC22A9 Double Nickase Plasmid (h2) - sc-410252-NIC-2 from Santa Cruz Biotechnology
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SLC22A9 CRISPR Activation Plasmid (h) - sc-410252-ACT from Santa Cruz Biotechnology
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SLC22A9 CRISPR Activation Plasmid (h2) - sc-410252-ACT-2 from Santa Cruz Biotechnology
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SLC22A9 Lentiviral Activation Particles (h) - sc-410252-LAC from Santa Cruz Biotechnology
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SLC22A9 Lentiviral Activation Particles (h2) - sc-410252-LAC-2 from Santa Cruz Biotechnology
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SLC22A9 siRNA (h) - sc-96491 from Santa Cruz Biotechnology
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SLC22A9 shRNA Plasmid (h) - sc-96491-SH from Santa Cruz Biotechnology
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SLC22A9 shRNA (h) Lentiviral Particles - sc-96491-V from Santa Cruz Biotechnology
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SLC22A9 RNAi - H00114571-R01 from Novus Biologicals
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MISSION® esiRNA - EHU128401 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19473 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19473 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02941 from Sigma-Aldrich
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SLC22A9 siRNA (Human) - CRJ4359 from Cohesion Biosciences
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SLC22A9 - MBS8227155 from MyBioSource
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shRNA set against Human SLC22A9 (NM_080866.2) - SHH409264 from Creative biogene
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Human SLC22A9 siRNA - orb274860 from Biorbyt
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SLC22A9 shRNA Plasmid (Human) - CHJ4359 from Cohesion Biosciences
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SLC22A9 miRNA 3'UTR clone - MiUTR1H-09467 from Creative biogene
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