| Gene Symbol | SLC23A1 |
|---|---|
| Entrez Gene | 9963 |
| Alt Symbol | SLC23A2, SVCT1, YSPL3 |
| Species | Human |
| Gene Type | protein-coding |
| Description | solute carrier family 23 (ascorbic acid transporter), member 1 |
| Other Description | Na(+)/L-ascorbic acid transporter 1|hSVCT1|sodium-dependent vitamin C transporter 1|sodium-dependent vitamin C transporter-1|solute carrier family 23 (nucleobase transporters), member 1|solute carrier family 23 (nucleobase transporters), member 2|solute carrier family 23 member 1|yolk sac permease-like molecule 3 |
| Swissprots | Q9UI39 Q8WWB6 O95191 Q9UHI7 Q9UGH4 |
| Accessions | AAK97398 EAW62106 Q9UHI7 AF058317 AAC78804 AF098277 AAF22490 AF170911 AAF24759 AI478520 AJ250807 CAC15384 AJ269477 CAB58119 AK092655 BAG52585 AK290789 BAF83478 AK298337 BAG60585 AK300935 BAG62564 BC019225 AAH19225 BC050261 AAH50261 DA385445 XM_005272148 XP_005272205 XM_005272149 XP_005272206 XM_006714741 XP_006714804 XM_011543765 XP_011542067 XM_011543766 XP_011542068 XM_011543767 XP_011542069 XM_011543768 XP_011542070 XM_011543769 XP_011542071 NM_005847 NP_005838 NM_152685 NP_689898 |
| Function | Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate. |
| Subcellular Location | Cell membrane {ECO:0000269|PubMed:19379732}; Multi-pass membrane protein {ECO:0000269|PubMed:19379732}. |
| Tissue Specificity | Highly expressed in adult small intestine, kidney, thymus, ovary, colon, prostate and liver, and in fetal kidney, liver and thymus. |
| Top Pathways | Vitamin digestion and absorption |