| Gene Symbol |
SLC23A1
|
| Entrez Gene |
9963
|
| Alt Symbol |
SLC23A2, SVCT1, YSPL3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 23 (ascorbic acid transporter), member 1
|
| Other Description |
Na(+)/L-ascorbic acid transporter 1|hSVCT1|sodium-dependent vitamin C transporter 1|sodium-dependent vitamin C transporter-1|solute carrier family 23 (nucleobase transporters), member 1|solute carrier family 23 (nucleobase transporters), member 2|solute carrier family 23 member 1|yolk sac permease-like molecule 3
|
| Swissprots |
Q9UI39 Q8WWB6 O95191 Q9UHI7 Q9UGH4
|
| Accessions |
AAK97398 EAW62106 Q9UHI7 AF058317 AAC78804 AF098277 AAF22490 AF170911 AAF24759 AI478520 AJ250807 CAC15384 AJ269477 CAB58119 AK092655 BAG52585 AK290789 BAF83478 AK298337 BAG60585 AK300935 BAG62564 BC019225 AAH19225 BC050261 AAH50261 DA385445 XM_005272148 XP_005272205 XM_005272149 XP_005272206 XM_006714741 XP_006714804 XM_011543765 XP_011542067 XM_011543766 XP_011542068 XM_011543767 XP_011542069 XM_011543768 XP_011542070 XM_011543769 XP_011542071 NM_005847 NP_005838 NM_152685 NP_689898
|
| Function |
Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:19379732}; Multi-pass membrane protein {ECO:0000269|PubMed:19379732}.
|
| Tissue Specificity |
Highly expressed in adult small intestine, kidney, thymus, ovary, colon, prostate and liver, and in fetal kidney, liver and thymus.
|
| Top Pathways |
Vitamin digestion and absorption
|