| Gene Symbol |
LSG1
|
| Entrez Gene |
55341
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
large 60S subunit nuclear export GTPase 1
|
| Other Description |
hLsg1|large subunit GTPase 1 homolog
|
| Swissprots |
Q9H089 A6NI18 A0JLT4 Q9NUK8 Q7L9H8 A0PJK3
|
| Accessions |
EAW78035 EAW78036 EAW78037 EAW78038 EAW78039 Q9H089 AK002163 BAA92116 AK130804 AK225094 AL136897 CAB66831 AM392577 CAL37455 AW748476 BC015042 AAH15042 BC040119 AAH40119 BC058891 BC068500 AAH68500 BQ009975 DA101432 DA414880 NM_018385 NP_060855
|
| Function |
GTPase required for the XPO1/CRM1-mediated nuclear export of the 60S ribosomal subunit. Probably acts by mediating the release of NMD3 from the 60S ribosomal subunit after export into the cytoplasm (Probable). {ECO:0000305|PubMed:16209721}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:16209721}. Endoplasmic reticulum {ECO:0000269|PubMed:16209721}. Nucleus, Cajal body {ECO:0000269|PubMed:16209721}. Note=Shuttles between the Cajal bodies in the nucleus and the endoplasmic reticulum.
|
| Top Pathways |
Ribosome biogenesis in eukaryotes
|