| Gene Symbol |
DYNLT3
|
| Entrez Gene |
6990
|
| Alt Symbol |
RP3, TCTE1L, TCTEX1L
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
dynein, light chain, Tctex-type 3
|
| Other Description |
dynein light chain Tctex-type 3|protein 91/23
|
| Swissprots |
P51808 Q6ICS3
|
| Accessions |
CAV30714 EAW59452 P51808 AK311851 BAG34793 BC000968 AAH00968 CR450320 CAG29316 CR542213 CAG47009 DA342302 DB492712 GQ129368 ACT64502 GQ129369 ACT64503 U02556 AAA57444 NM_006520 NP_006511
|
| Function |
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus. Cytoplasm, cytoskeleton. Chromosome, centromere, kinetochore. Note=Colocalizes with BUB3 at kinetochores specifically during prometaphase.
|
![Western Blot: DYNLT3 Overexpression Lysate (Adult Normal) [NBL1-10074] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for DYNLT3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9797_DYNLT3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-10074-img0002.jpg)