Gene Symbol | DYNLT3 |
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Entrez Gene | 6990 |
Alt Symbol | RP3, TCTE1L, TCTEX1L |
Species | Human |
Gene Type | protein-coding |
Description | dynein, light chain, Tctex-type 3 |
Other Description | dynein light chain Tctex-type 3|protein 91/23 |
Swissprots | P51808 Q6ICS3 |
Accessions | CAV30714 EAW59452 P51808 AK311851 BAG34793 BC000968 AAH00968 CR450320 CAG29316 CR542213 CAG47009 DA342302 DB492712 GQ129368 ACT64502 GQ129369 ACT64503 U02556 AAA57444 NM_006520 NP_006511 |
Function | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus. Cytoplasm, cytoskeleton. Chromosome, centromere, kinetochore. Note=Colocalizes with BUB3 at kinetochores specifically during prometaphase. |
Tctex1L CRISPR/Cas9 KO Plasmid (h) - sc-416958 from Santa Cruz Biotechnology
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Tctex1L HDR Plasmid (h) - sc-416958-HDR from Santa Cruz Biotechnology
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Tctex1L Double Nickase Plasmid (h) - sc-416958-NIC from Santa Cruz Biotechnology
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Tctex1L Double Nickase Plasmid (h2) - sc-416958-NIC-2 from Santa Cruz Biotechnology
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Tctex1L CRISPR Activation Plasmid (h) - sc-416958-ACT from Santa Cruz Biotechnology
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Tctex1L CRISPR Activation Plasmid (h2) - sc-416958-ACT-2 from Santa Cruz Biotechnology
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Tctex1L Lentiviral Activation Particles (h) - sc-416958-LAC from Santa Cruz Biotechnology
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Tctex1L Lentiviral Activation Particles (h2) - sc-416958-LAC-2 from Santa Cruz Biotechnology
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Tctex1L siRNA (h) - sc-90988 from Santa Cruz Biotechnology
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Tctex1L shRNA Plasmid (h) - sc-90988-SH from Santa Cruz Biotechnology
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Tctex1L shRNA (h) Lentiviral Particles - sc-90988-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU105521 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7593 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7593 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12771 from Sigma-Aldrich
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DYNLT3 siRNA (Human) - CRH4772 from Cohesion Biosciences
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DYNLT3 - MBS8227802 from MyBioSource
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shRNA set against Human DYNLT3 (NM_006520.2) - SHH282253 from Creative biogene
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Human DYNLT3 siRNA - orb265274 from Biorbyt
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DYNLT3 shRNA Plasmid (Human) - CHH4772 from Cohesion Biosciences
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DYNLT3 miRNA 3'UTR clone - MiUTR3H-02694 from Creative biogene
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