Gene Symbol |
PTGFRN
|
Entrez Gene |
5738
|
Alt Symbol |
CD315, CD9P-1, EWI-F, FPRP, SMAP-6
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
prostaglandin F2 receptor inhibitor
|
Other Description |
CD9 partner 1|glu-Trp-Ile EWI motif-containing protein F|prostaglandin F2 receptor negative regulator|prostaglandin F2-alpha receptor regulatory protein|prostaglandin F2-alpha receptor-associated protein
|
Swissprots |
Q5VVU9 Q9P2B2 Q8N2K6
|
Accessions |
EAW56662 EAW56663 Q9P2B2 AA045111 AB014734 BAB20271 AB037857 BAA92674 AK001863 AK024785 AK074637 BAC11104 BC022235 BC042164 BC063317 BC098142 AAH98142 BC114520 AAI14521 BC139718 AAI39719 BC152454 AAI52455 BC168364 AAI68364 DA572787 NM_020440 NP_065173
|
Function |
Inhibits the binding of prostaglandin F2-alpha (PGF2- alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur (By similarity). {ECO:0000250}.
|
Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
|