Gene Symbol | PTGFRN |
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Entrez Gene | 5738 |
Alt Symbol | CD315, CD9P-1, EWI-F, FPRP, SMAP-6 |
Species | Human |
Gene Type | protein-coding |
Description | prostaglandin F2 receptor inhibitor |
Other Description | CD9 partner 1|glu-Trp-Ile EWI motif-containing protein F|prostaglandin F2 receptor negative regulator|prostaglandin F2-alpha receptor regulatory protein|prostaglandin F2-alpha receptor-associated protein |
Swissprots | Q5VVU9 Q9P2B2 Q8N2K6 |
Accessions | EAW56662 EAW56663 Q9P2B2 AA045111 AB014734 BAB20271 AB037857 BAA92674 AK001863 AK024785 AK074637 BAC11104 BC022235 BC042164 BC063317 BC098142 AAH98142 BC114520 AAI14521 BC139718 AAI39719 BC152454 AAI52455 BC168364 AAI68364 DA572787 NM_020440 NP_065173 |
Function | Inhibits the binding of prostaglandin F2-alpha (PGF2- alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur (By similarity). {ECO:0000250}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. |
CD9P-1 CRISPR/Cas9 KO Plasmid (h) - sc-404449 from Santa Cruz Biotechnology
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CD9P-1 HDR Plasmid (h) - sc-404449-HDR from Santa Cruz Biotechnology
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CD9P-1 Double Nickase Plasmid (h) - sc-404449-NIC from Santa Cruz Biotechnology
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CD9P-1 Double Nickase Plasmid (h2) - sc-404449-NIC-2 from Santa Cruz Biotechnology
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CD9P-1 CRISPR Activation Plasmid (h) - sc-404449-ACT from Santa Cruz Biotechnology
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CD9P-1 CRISPR Activation Plasmid (h2) - sc-404449-ACT-2 from Santa Cruz Biotechnology
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CD9P-1 Lentiviral Activation Particles (h) - sc-404449-LAC from Santa Cruz Biotechnology
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CD9P-1 Lentiviral Activation Particles (h2) - sc-404449-LAC-2 from Santa Cruz Biotechnology
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CD9P-1 siRNA (h) - sc-78979 from Santa Cruz Biotechnology
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CD9P-1 shRNA Plasmid (h) - sc-78979-SH from Santa Cruz Biotechnology
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CD9P-1 shRNA (h) Lentiviral Particles - sc-78979-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU137071 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17672 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17672 from Sigma-Aldrich
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PTGFRN siRNA (Human) - CRH3880 from Cohesion Biosciences
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shRNA set against Human PTGFRN (NM_020440.2) - SHH386076 from Creative biogene
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shRNA set against Human PTGFRN(NM_020440.2) - SHR106688 from Creative biogene
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PTGFRN shRNA Plasmid (Human) - CHH3880 from Cohesion Biosciences
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PTGFRN miRNA 3'UTR clone - MiUTR4H-TG07190 from Creative biogene
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