Gene Symbol | GFRA3 |
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Entrez Gene | 2676 |
Alt Symbol | GDNFR3 |
Species | Human |
Gene Type | protein-coding |
Description | GDNF family receptor alpha 3 |
Other Description | GDNF family receptor alpha-3|GDNF receptor alpha-3|GDNFR-alpha-3|GFR-alpha-3|GPI-linked receptor|glial cell line-derived neurotrophic factor receptor alpha-3 |
Swissprots | Q6UW20 B4DMY9 O60609 B2RA36 Q8IUZ2 |
Accessions | CAM55952 EAW62152 EAW62153 O60609 AF051767 AAC24355 AF086292 AK297693 BAG60051 AK314022 BAG36733 AW020606 AY358997 AAQ89356 AY359037 AAQ89396 BC037951 AAH37951 DQ890850 ABM81776 DQ894004 ABM84930 FJ200487 ACO54884 NM_001496 NP_001487 |
Function | Receptor for the glial cell line-derived neurotrophic factor, ARTN (artemin). Mediates the artemin-induced autophosphorylation and activation of the RET receptor tyrosine kinase. {ECO:0000269|PubMed:9883723}. |
Subcellular Location | Cell membrane; Lipid-anchor, GPI-anchor. |
Tissue Specificity | Widely expressed in adult and fetus which exhibit a similar pattern. Essentially not expressed in the central nervous system, but highly expressed in several sensory and sympathetic ganglia of the peripheral nervous system. Moderate expression in many non-neuronal tissues, particularly those of the digestive and urogenital systems, but high expression in stomach and appendix. Several types of glandular tissues show low expression. Very low or no expression detected in the hematopoietic system. {ECO:0000269|PubMed:9576965}. |
GFR alpha 3 peptide - ab6100 from Abcam
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Human GFR alpha 3 full length protein - ab158514 from Abcam
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Human GFR alpha 3 full length protein - ab174556 from Abcam
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GFRA3 Antibody Blocking Peptide - LS-E4091 from LifeSpan Bioscience
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GFRA3 Antibody Blocking Peptide - LS-E29850 from LifeSpan Bioscience
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GFR alpha-3/GDNF R alpha-3 Recombinant Protein - H00002676-P01 from Novus Biologicals
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Recombinant Human GFR alpha-3/GDNF R alpha-3 Protein - NBP2-23072 from Novus Biologicals
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GFR alpha-3/GDNF R alpha-3 Blocking Peptide - NBP1-77035PEP from Novus Biologicals
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GFRA3-Antibody-Center-Blocking-Peptide - BP16331c from Abgent, a WuXi AppTec company
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Recombinant Human GFR alpha-3 Fc Chimera, CF - 670-FR-100 from R&D Systems
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Recombinant Human GFR alpha-3 Fc Chimera (CHO-expressed), CF - 7269-FR-100 from R&D Systems
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Human GFRA3 Fc His tag protein - orb83623 from Biorbyt
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Human GFRA3 His tag protein - orb83693 from Biorbyt
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GFRA3 protein (His tag) - 80R-3531 from Fitzgerald
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GFRA3 / GDNFR-alpha 3 (32-374, His-tag) - AR51219PU-N from Acris Antibodies
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GFRA3 / GDNFR-alpha 3 (32-374, His-tag) - AR51219PU-S from Acris Antibodies
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GFRA3 / GDNFR-alpha 3 - H00002676-P01-02 from Acris Antibodies
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GFRA3, 32-374aa, Human, His tag, E.coli - 01-P2398 from ARP American Research Products
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GFRA3 fusion protein - Ag13253 from Proteintech Group
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GFRA3 fusion protein - ag13250 from Proteintech Group
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Recombinant Human GDNF Family Receptor Alpha 3 - GFRA3-1620H from Creative Biomart
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Recombinant Human GFRA3, His tagged - GFRA3-3153H from Creative Biomart
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Recombinant Human GFRA3, Fc-His tagged - GFRA3-3242H from Creative Biomart
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Recombinant Human GDNF family receptor alpha 3, His-tagged - GFRA3-315H from Creative Biomart
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Recombinant Human GFRA3, Fc Chimera - GFRA3-237H from Creative Biomart
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