| Gene Symbol |
PDHX
|
| Entrez Gene |
8050
|
| Alt Symbol |
DLDBP, E3BP, OPDX, PDX1, proX
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
pyruvate dehydrogenase complex, component X
|
| Other Description |
dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex|lipoyl-containing pyruvate dehydrogenase complex component X|pyruvate dehydrogenase complex, E3-binding protein subunit|pyruvate dehydrogenase complex, lipoyl-containing component X|pyruvate dehydrogenase protein X component, mitochondrial
|
| Swissprots |
B4DW62 Q96FV8 D3DR11 O60221 E9PBP7 Q99783 E9PB14 O00330
|
| Accessions |
CAC18649 EAW68158 EAW68159 EAW68160 O00330 AA282215 AF001437 AAB66315 AF052166 AK057123 AK301384 BAG62924 AK312463 BAG35370 BC010389 AAH10389 BI915296 BX648910 DA573433 JF432191 ADZ15408 U79296 AAB50223 U82328 AAC39661 Y13145 CAA73606 XM_011520390 XP_011518692 NM_001135024 NP_001128496 NM_001166158 NP_001159630 NM_003477 NP_003468
|
| Function |
Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex.
|
| Subcellular Location |
Mitochondrion matrix.
|
![Western Blot: PDHX Overexpression Lysate (Adult Normal) [NBL1-14243] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PDHX.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7579_PDHX%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-14243-img0002.jpg)