| Gene Symbol |
SGCG
|
| Entrez Gene |
6445
|
| Alt Symbol |
A4, DAGA4, DMDA, DMDA1, LGMD2C, MAM, SCARMD2, SCG3, TYPE
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
|
| Other Description |
35 kDa dystrophin-associated glycoprotein|35DAG|35kD dystrophin-associated glycoprotein|gamma sarcoglycan|gamma-SG|gamma-sarcoglycan
|
| Swissprots |
Q32M32 Q5T9J6 Q13326
|
| Accessions |
AAD13475 EAX08320 EAX08321 Q13326 AK290620 BAF83309 AK316579 BAG38167 BC074777 AAH74777 BC074778 AAH74778 BC109321 AAI09322 DA897096 U34976 AAC50269 XM_005266505 XP_005266562 XM_006719861 XP_006719924 NM_000231 NP_000222
|
| Function |
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
|
| Subcellular Location |
Cell membrane, sarcolemma {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}.
|
| Tissue Specificity |
Expressed in skeletal and heart muscle.
|
| Top Pathways |
Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy
|