| Gene Symbol |
RSC1A1
|
| Entrez Gene |
6248
|
| Alt Symbol |
RS1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
regulatory solute carrier protein, family 1, member 1
|
| Other Description |
regulatory solute carrier protein family 1 member 1|transporter regulator RS1
|
| Swissprots |
B2RBP5 Q92681
|
| Accessions |
CAA58058 CAL64679 CAL64683 EAW51744 Q92681 AK314753 BAG37292 BC152937 AAI52938 NM_006511 NP_006502
|
| Function |
Mediates transcriptional and post-transcriptional regulation of SLC5A1. Inhibits a dynamin and PKC-dependent exocytotic pathway of SLC5A1. Also involved in transcriptional regulation of SLC22A2. Exhibits glucose-dependent, short-term inhibition of SLC5A1 and SLC22A2 by inhibiting the release of vesicles from the trans-Golgi network. {ECO:0000269|PubMed:14724758, ECO:0000269|PubMed:16788146, ECO:0000269|PubMed:8836035}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:16788147}. Nucleus {ECO:0000269|PubMed:16788147}. Golgi apparatus, trans- Golgi network {ECO:0000269|PubMed:16788147}. Note=Localizes at the inner side of the plasma membrane.
|
| Tissue Specificity |
Expressed in small intestine, kidney and brain. {ECO:0000269|PubMed:8836035}.
|
