Gene Symbol | RSC1A1 |
---|---|
Entrez Gene | 6248 |
Alt Symbol | RS1 |
Species | Human |
Gene Type | protein-coding |
Description | regulatory solute carrier protein, family 1, member 1 |
Other Description | regulatory solute carrier protein family 1 member 1|transporter regulator RS1 |
Swissprots | B2RBP5 Q92681 |
Accessions | CAA58058 CAL64679 CAL64683 EAW51744 Q92681 AK314753 BAG37292 BC152937 AAI52938 NM_006511 NP_006502 |
Function | Mediates transcriptional and post-transcriptional regulation of SLC5A1. Inhibits a dynamin and PKC-dependent exocytotic pathway of SLC5A1. Also involved in transcriptional regulation of SLC22A2. Exhibits glucose-dependent, short-term inhibition of SLC5A1 and SLC22A2 by inhibiting the release of vesicles from the trans-Golgi network. {ECO:0000269|PubMed:14724758, ECO:0000269|PubMed:16788146, ECO:0000269|PubMed:8836035}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:16788147}. Nucleus {ECO:0000269|PubMed:16788147}. Golgi apparatus, trans- Golgi network {ECO:0000269|PubMed:16788147}. Note=Localizes at the inner side of the plasma membrane. |
Tissue Specificity | Expressed in small intestine, kidney and brain. {ECO:0000269|PubMed:8836035}. |
RSC1A1 CRISPR/Cas9 KO Plasmid (h) - sc-408770 from Santa Cruz Biotechnology
|
||||||||
RSC1A1 HDR Plasmid (h) - sc-408770-HDR from Santa Cruz Biotechnology
|
||||||||
RSC1A1 Double Nickase Plasmid (h) - sc-408770-NIC from Santa Cruz Biotechnology
|
||||||||
RSC1A1 Double Nickase Plasmid (h2) - sc-408770-NIC-2 from Santa Cruz Biotechnology
|
||||||||
RSC1A1 CRISPR Activation Plasmid (h) - sc-408770-ACT from Santa Cruz Biotechnology
|
||||||||
RSC1A1 CRISPR Activation Plasmid (h2) - sc-408770-ACT-2 from Santa Cruz Biotechnology
|
||||||||
RSC1A1 Lentiviral Activation Particles (h) - sc-408770-LAC from Santa Cruz Biotechnology
|
||||||||
RSC1A1 Lentiviral Activation Particles (h2) - sc-408770-LAC-2 from Santa Cruz Biotechnology
|
||||||||
RSC1A1 siRNA (h) - sc-88001 from Santa Cruz Biotechnology
|
||||||||
RSC1A1 shRNA Plasmid (h) - sc-88001-SH from Santa Cruz Biotechnology
|
||||||||
RSC1A1 shRNA (h) Lentiviral Particles - sc-88001-V from Santa Cruz Biotechnology
|
||||||||
RSC1A1 RNAi - H00006248-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU230881 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN18707 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18707 from Sigma-Aldrich
|
||||||||
RSC1A1 siRNA (Human) - CRH4207 from Cohesion Biosciences
|
||||||||
RSC1A1 - MBS8205202 from MyBioSource
|
||||||||
shRNA set against Human RSC1A1 (NM_006511.1) - SHH400176 from Creative biogene
|
||||||||
Human RSC1A1 siRNA - orb264709 from Biorbyt
|
||||||||
RSC1A1 shRNA Plasmid (Human) - CHH4207 from Cohesion Biosciences
|
||||||||
RSC1A1 miRNA 3'UTR clone - MiUTR1H-09053 from Creative biogene
|