| Gene Symbol |
DENND1C
|
| Entrez Gene |
79958
|
| Alt Symbol |
FAM31C
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
DENN/MADD domain containing 1C
|
| Other Description |
DENN domain-containing protein 1C|connecdenn 3|family with sequence similarity 31, member C
|
| Swissprots |
Q9H5Z2 Q8IV53 Q8NDB1 D3PFD4 B4E051
|
| Accessions |
EAW69080 EAW69081 EAW69082 Q8IV53 AA521476 AK026410 BAB15475 AK055820 BAG51578 AK225623 AK303226 BAG64313 AK303509 BAH13977 AL713770 AL834293 CAD38966 BC033437 AAH33437 BE674790 BK006959 DAA12501 BX647304 DC378383 XM_006722905 XP_006722968 XM_006722906 XP_006722969 XM_011528318 XP_011526620 NM_001290331 NP_001277260 NM_024898 NP_079174
|
| Function |
Guanine nucleotide exchange factor (GEF) which may activate RAB8A, RAB13 and RAB35. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. {ECO:0000269|PubMed:20154091, ECO:0000269|PubMed:20937701}.
|
| Subcellular Location |
Cytoplasm, cytosol {ECO:0000250}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000250}.
|
![Western Blot: DENND1C Overexpression Lysate (Adult Normal) [NBP2-06269] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for DENND1C.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6743_DENND1C%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06269-img0001.jpg)