Gene Symbol | DENND1C |
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Entrez Gene | 79958 |
Alt Symbol | FAM31C |
Species | Human |
Gene Type | protein-coding |
Description | DENN/MADD domain containing 1C |
Other Description | DENN domain-containing protein 1C|connecdenn 3|family with sequence similarity 31, member C |
Swissprots | Q9H5Z2 Q8IV53 Q8NDB1 D3PFD4 B4E051 |
Accessions | EAW69080 EAW69081 EAW69082 Q8IV53 AA521476 AK026410 BAB15475 AK055820 BAG51578 AK225623 AK303226 BAG64313 AK303509 BAH13977 AL713770 AL834293 CAD38966 BC033437 AAH33437 BE674790 BK006959 DAA12501 BX647304 DC378383 XM_006722905 XP_006722968 XM_006722906 XP_006722969 XM_011528318 XP_011526620 NM_001290331 NP_001277260 NM_024898 NP_079174 |
Function | Guanine nucleotide exchange factor (GEF) which may activate RAB8A, RAB13 and RAB35. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. {ECO:0000269|PubMed:20154091, ECO:0000269|PubMed:20937701}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000250}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000250}. |
DENND1C CRISPR/Cas9 KO Plasmid (h) - sc-406702 from Santa Cruz Biotechnology
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DENND1C HDR Plasmid (h) - sc-406702-HDR from Santa Cruz Biotechnology
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DENND1C Double Nickase Plasmid (h) - sc-406702-NIC from Santa Cruz Biotechnology
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DENND1C Double Nickase Plasmid (h2) - sc-406702-NIC-2 from Santa Cruz Biotechnology
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DENND1C CRISPR Activation Plasmid (h) - sc-406702-ACT from Santa Cruz Biotechnology
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DENND1C CRISPR Activation Plasmid (h2) - sc-406702-ACT-2 from Santa Cruz Biotechnology
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DENND1C Lentiviral Activation Particles (h) - sc-406702-LAC from Santa Cruz Biotechnology
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DENND1C Lentiviral Activation Particles (h2) - sc-406702-LAC-2 from Santa Cruz Biotechnology
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DENND1C siRNA (h) - sc-97386 from Santa Cruz Biotechnology
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DENND1C shRNA Plasmid (h) - sc-97386-SH from Santa Cruz Biotechnology
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DENND1C shRNA (h) Lentiviral Particles - sc-97386-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU103121 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7137 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7137 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01963 from Sigma-Aldrich
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DENND1C siRNA (Human) - CRJ2692 from Cohesion Biosciences
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DENND1C - MBS8201586 from MyBioSource
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shRNA set against Human DENND1C (NM_024898.2) - SHH277025 from Creative biogene
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shRNA set against Human DENND1C(NM_024898.2) - SHH001289 from Creative biogene
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Human DENND1C siRNA - orb273193 from Biorbyt
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DENND1C shRNA Plasmid (Human) - CHJ2692 from Cohesion Biosciences
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DENND1C miRNA 3'UTR clone - MiUTR1H-02771 from Creative biogene
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