| Gene Symbol |
GRIK5
|
| Entrez Gene |
2901
|
| Alt Symbol |
EAA2, GRIK2, GluK5, KA2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
glutamate receptor, ionotropic, kainate 5
|
| Other Description |
excitatory amino acid receptor 2|glutamate receptor KA2|glutamate receptor ionotropic, kainate 5
|
| Swissprots |
Q16478 Q8WWG8
|
| Accessions |
EAW57090 EAW57091 Q16478 AJ249209 CAC80547 BC037358 BC052975 BC131717 BC168375 AAI68375 BM152516 CA432656 S40369 AAB22591 XM_005258821 XP_005258878 XM_011526862 XP_011525164 XM_011526863 XP_011525165 XM_011526864 XP_011525166 XM_011526865 XP_011525167 XM_011526866 XP_011525168 XM_011526867 XP_011525169 XM_011526868 XP_011525170 XM_011526869 XP_011525171 XM_011526870 XP_011525172 XM_011526871 XP_011525173 XR_935810 NM_001301030 NP_001287959 NM_002088 NP_002079
|
| Function |
Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds kainate > quisqualate > domoate > L- glutamate >> AMPA >> NMDA = 1S,3R-ACPD.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Glutamatergic synapse, Neuroactive ligand-receptor interaction
|