| Gene Symbol |
UCK1
|
| Entrez Gene |
83549
|
| Alt Symbol |
URK1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
uridine-cytidine kinase 1
|
| Other Description |
UCK 1|cytidine monophosphokinase 1|uridine monophosphokinase 1
|
| Swissprots |
Q9HA47 Q5JT13 Q5JT09 Q96BJ0 Q6IA74 Q5JT12 Q5JT10
|
| Accessions |
CBX51398 EAW87979 EAW87980 EAW87981 EAW87982 EAW87983 EAW87984 Q9HA47 AA809511 AF125106 AAL75943 AF237290 AAK28324 AF254133 AAK49122 AK022317 BAB14010 AK057848 AK295471 BAG58400 AK307475 BC015547 AAH15547 BC091495 AAH91495 BI770572 CR457281 CAG33562 DA598285 XM_005272224 XP_005272281 XM_005272225 XP_005272282 XM_011519072 XP_011517374 XR_246602 XR_246603 NM_001135954 NP_001129426 NM_001261450 NP_001248379 NM_001261451 NP_001248380 NM_031432 NP_113620
|
| Function |
Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor. Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4- thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)- benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5- methylcytidine, and N(4)-anisoylcytidine.
|
| Tissue Specificity |
Ubiquitous.
|
| Top Pathways |
Drug metabolism - other enzymes, Pyrimidine metabolism
|
