| Gene Symbol |
HIST1H1E
|
| Entrez Gene |
3008
|
| Alt Symbol |
H1.4, H1E, H1F4, H1s-4, dJ221C16.5
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
histone cluster 1, H1e
|
| Other Description |
H1 histone family, member 4|histone 1, H1e|histone H1.4|histone H1b|histone H1s-4
|
| Swissprots |
Q4VB25 P10412
|
| Accessions |
AAA63187 AAN06702 EAW55534 P10412 AK313681 BAG36431 BC055095 BC096168 AAH96168 BC096169 AAH96169 BC096170 AAH96170 BC099632 AAH99632 EF065554 ABN72276 EF065555 ABN72277 NM_005321 NP_005312
|
| Function |
Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus. Chromosome. Note=Mainly localizes in heterochromatin. Dysplays a punctuate staining pattern in the nucleus.
|
![Western Blot: Histone H1.4 Overexpression Lysate (Adult Normal) [NBL1-11555] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Histone H1.4.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4711_Histone%2520H1.4%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11555-img0002.jpg)