NPAS2

Gene Symbol NPAS2
Entrez Gene 4862
Alt Symbol MOP4, PASD4, bHLHe9
Species Human
Gene Type protein-coding
Description neuronal PAS domain protein 2
Other Description PAS domain-containing protein 4|basic-helix-loop-helix-PAS protein MOP4|class E basic helix-loop-helix protein 9|member of PAS protein 4|member of PAS superfamily 4|neuronal PAS domain-containing protein 2|neuronal PAS2
Swissprots Q99743 Q99629 Q86V96 Q53SQ3 Q4ZFV9
Accessions AAX88966 AAY14822 ABM64214 EAX01830 EAX01831 EAX01832 EAX01833 EAX01834 EAX01835 Q99743 AK026791 BAB15554 AK091939 AK095806 AK128586 AK226093 AK294733 BAH11862 BC028107 AAH28107 BC035412 BC051351 AAH51351 BC072383 AAH72383 BM724652 BX640699 KJ534892 AHW56532 U51625 AAC51211 U77970 AAB47250 XM_005263953 XP_005264010 XM_005263954 XP_005264011 XM_005263957 XP_005264014 XM_005263959 XP_005264016 XM_005263960 XP_005264017 XM_005263961 XP_005264018 XM_011511242 XP_011509544 XM_011511243 XP_011509545 XR_922928 NM_002518 NP_002509
Function Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time- keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal function. Consists of two major components: the central clock, residing in the suprachiasmatic nucleus (SCN) of the brain, and the peripheral clocks that are present in nearly every tissue and organ system. Both the central and peripheral clocks can be reset by environmental cues, also known as Zeitgebers (German for 'timegivers'). The predominant Zeitgeber for the central clock is light, which is sensed by retina and
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981, ECO:0000269|PubMed:14645221}.
Top Pathways Circadian rhythm

NPAS2 (H-20) - sc-13901 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NPAS2 (H-270) - sc-28708 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

NPAS2 (K-17) - sc-13900 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NPAS2 (FT-68) - sc-134404 from Santa Cruz Biotechnology

Prices $295.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
NPAS2 (FT-68): sc-134404. Western blot analysis of NPAS2 expression in human NPAS2 transfected (A) and non-transfected (B) 293T whole cell lysates.

Anti-NPAS2 antibody - ab137601 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-NPAS2 antibody (ab137601) at 1/1000 dilutionLane 1 : H1299 whole cell lysateLane 2 : Hela whole cell lysateLane 3 : Hep G2 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-NPAS2 antibody - ab168935 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-NPAS2 antibody (ab168935) at 1 µg/mlLane 1 : NPAS2-transfected 293T cell lysateLane 2 : non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-NPAS2 antibody - ab55833 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-NPAS2 antibody (ab55833) at 1/500 dilution + Mouse brain whole tissue lysate at 25 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab6721) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-NPAS2 antibody - ChIP Grade - ab157165 from Abcam

Host Rabbit
Clonality Polyclonal
Total extracts from Human HeLa cells were immunoprecipitated (Lane 1) with IgG or anti-NPAS2 (ab157165 Lane 2) under the cross-linked chromatin immunoprecipitation (ChIP) conditions; followed by WB with ab157165 at room temperature for 2 hours.

Anti-NPAS2 Antibody (N-Terminus) - LS-C46808 from LifeSpan Bioscience

Prices $295.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-NPAS2 Antibody (aa1-824) - LS-C130816 from LifeSpan Bioscience

Prices $445.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-NPAS2 Antibody (aa1-30, AP) - LS-C264589 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NPAS2 Antibody (aa1-30, APC) - LS-C264590 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NPAS2 Antibody (aa1-30, FITC) - LS-C264592 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NPAS2 Antibody (aa1-30, Azide-free, HRP) - LS-C264593 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NPAS2 Antibody (aa1-30, PE) - LS-C264594 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NPAS2 Antibody (aa403-448) - LS-C313859 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-NPAS2 Antibody (aa1-30) - LS-C323408 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NPAS2 Antibody (C-Terminus) - LS-C116020 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
NPAS2 antibody LS-C116020 Western blot of Mouse Heart lysate.

Anti-NPAS2 Antibody (clone 6C9) - LS-C197796 from LifeSpan Bioscience

Prices $355.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 6C9
Western Blot analysis of NPAS2 expression in transfected 293T cell line by NPAS2 monoclonal antibody (M03), clone 6C9.Lane 1: NPAS2 transfected lysate(91.8 KDa).Lane 2: Non-transfected lysate.

Anti-NPAS2 Antibody (C-Terminus) - LS-C80184 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-NPAS2 Antibody (aa351-400) - LS-C116021 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
NPAS2 antibody LS-C116021 Western blot of Mouse Muscle lysate.

Anti-NPAS2 Antibody (N-Terminus) - LS-C80183 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Transfected 293T cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-NPAS2 Antibody (aa1-30) - LS-C162954 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Fluorescent confocal image of MCF-7 cell stained with NPAS2 Antibody. MCF-7 cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with NPAS2 primary antibody (1:25, 1 h at 37°C). For secondary antibody, Alexa Fluor 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37°C). Cytoplasmic actin was counterstained with Alexa Fluor 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37°C). Nuclei were counterstained with DAPI (blue) (10 ug/ml, 10 min). NPAS2 immunoreactivity is localized to Nucleus significantly.

Anti-NPAS2 Antibody (aa1-30, Biotin) - LS-C264591 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

NPAS2 Antibody - NBP1-88612 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NPAS2 Antibody [NBP1-88612] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11Lane 2: Human cell line RT-4
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