CLCN2

Gene Symbol CLCN2
Entrez Gene 1181
Alt Symbol CIC-2, CLC2, ECA2, ECA3, EGI11, EGI3, EGMA, EJM6, EJM8, LKPAT, clC-2
Species Human
Gene Type protein-coding
Description chloride channel, voltage-sensitive 2
Other Description chloride channel 2|chloride channel protein 2
Swissprots B4DQT9 Q6IPA9 O14864 Q8WU13 B4DZ58 P51788 E9PCD2 E9PBD9
Accessions AAB34722 EAW78248 EAW78249 EAW78250 P51788 AA524434 AF026004 AAB88807 AK298952 BAG61051 AK302389 BAG63705 AK302759 BAG63970 AU132760 BC021578 AAH21578 BC072004 AAH72004 BX089717 DB533341 DC403930 XM_006713489 XP_006713552 XM_006713490 XP_006713553 XM_011512401 XP_011510703 XM_011512402 XP_011510704 NM_001171087 NP_001164558 NM_001171088 NP_001164559 NM_001171089 NP_001164560 NM_004366 NP_004357
Function Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. {ECO:0000269|PubMed:19153159, ECO:0000269|PubMed:19191339}.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Ubiquitously expressed. Moderately expressed in aortic and coronary vascular smooth muscle cells and expressed at a low level in aortic endothelial cells. {ECO:0000269|PubMed:10198195}.
Top Pathways Mineral absorption

CLC-2 (C-20) - sc-16430 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CLC-2 (C-20): sc-16430. Western blot analysis of CLC-2 expression in mouse heart tissue extract.

CLC-2 (D-6) - sc-377284 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CLC-2 (D-6): sc-377284. Western blot analysis of CLC-2 expression in A-10 (A) and U-87 MG (B) whole cell lysates and mouse heart tissue extract (C).

CLC-2 (H-90) - sc-20122 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CLC-2 (H-90): sc-20122. Immunoperoxidase staining of formalin fixed, paraffin-embedded human stomach tissue showing membrane and cytoplasmic staining of glandular cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

CLC-2 (P-16) - sc-16429 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CLC-2 (P-16): sc-16429. Western blot analysis of CLC-2 expression in mouse heart tissue extract.

CLC-2 (YY9) - sc-81871 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
CLC-2 (YY9): sc-81871. Western blot analysis of CLC-2 expression in HeLa nuclear extract.

Anti-CLCN2 antibody - ab192506 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CLCN2 antibody - ab130686 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-CLCN2 antibody (ab130686) at 1/100 dilution + HL60 cell line lysates at 35 µgdeveloped using the ECL technique

Anti-CLCN2 antibody - ab54664 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-CLCN2 antibody [EPR6492(2)] - ab154798 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6492(2)
All lanes : Anti-CLCN2 antibody [EPR6492(2)] (ab154798) at 1/1000 dilutionLane 1 : HT29 cell lysateLane 2 : HeLa cell lysateLysates/proteins at 10 µg per lane.

Anti-CLCN2 Antibody (C-Terminus) - LS-C6121 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-CLCN2 Antibody (C-Terminus) - LS-C6122 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-CLCN2 Antibody (aa38-388, clone 10B2253, Azide-free) - LS-C183520 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 10B2253

Anti-CLCN2 Antibody (aa208-237, AP) - LS-C254921 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLCN2 Antibody (aa208-237, Biotin) - LS-C254922 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLCN2 Antibody (aa208-237, APC) - LS-C254923 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLCN2 Antibody (aa208-237, FITC) - LS-C254924 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLCN2 Antibody (aa208-237, Azide-free, HRP) - LS-C254925 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLCN2 Antibody (aa208-237, PE) - LS-C254926 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLCN2 Antibody (aa208-237) - LS-C320413 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLCN2 Antibody - LS-C341924 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CLCN2 Antibody (aa738-751) IHC-plus™ - LS-B5141 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-CLCN2 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5141 concentration 3.75 ug/ml.

Anti-CLCN2 Antibody (Internal) - LS-C112963 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
CLCN2 antibody (0.3 ug/ml) staining of HeLa lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-CLCN2 Antibody - LS-C334513 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using CLCN2 antibody.

Anti-CLCN2 Antibody (aa208-237) - LS-C168805 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
CLCN2 Antibody western blot of mouse Neuro-2a cell line lysates (35 ug/lane). The CLCN2 antibody detected the CLCN2 protein (arrow).

Anti-CLCN2 Antibody (clone 3E1) - LS-C196930 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3E1
Western Blot analysis of CLCN2 expression in transfected 293T cell line by CLCN2 monoclonal antibody (M01), clone 3E1.Lane 1: CLCN2 transfected lysate(96.8 KDa).Lane 2: Non-transfected lysate.
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