Gene Symbol | CLCN2 |
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Entrez Gene | 1181 |
Alt Symbol | CIC-2, CLC2, ECA2, ECA3, EGI11, EGI3, EGMA, EJM6, EJM8, LKPAT, clC-2 |
Species | Human |
Gene Type | protein-coding |
Description | chloride channel, voltage-sensitive 2 |
Other Description | chloride channel 2|chloride channel protein 2 |
Swissprots | B4DQT9 Q6IPA9 O14864 Q8WU13 B4DZ58 P51788 E9PCD2 E9PBD9 |
Accessions | AAB34722 EAW78248 EAW78249 EAW78250 P51788 AA524434 AF026004 AAB88807 AK298952 BAG61051 AK302389 BAG63705 AK302759 BAG63970 AU132760 BC021578 AAH21578 BC072004 AAH72004 BX089717 DB533341 DC403930 XM_006713489 XP_006713552 XM_006713490 XP_006713553 XM_011512401 XP_011510703 XM_011512402 XP_011510704 NM_001171087 NP_001164558 NM_001171088 NP_001164559 NM_001171089 NP_001164560 NM_004366 NP_004357 |
Function | Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. {ECO:0000269|PubMed:19153159, ECO:0000269|PubMed:19191339}. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Ubiquitously expressed. Moderately expressed in aortic and coronary vascular smooth muscle cells and expressed at a low level in aortic endothelial cells. {ECO:0000269|PubMed:10198195}. |
Top Pathways | Mineral absorption |
CLC-2 (C-20) - sc-16430 from Santa Cruz Biotechnology
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CLC-2 (D-6) - sc-377284 from Santa Cruz Biotechnology
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CLC-2 (H-90) - sc-20122 from Santa Cruz Biotechnology
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CLC-2 (P-16) - sc-16429 from Santa Cruz Biotechnology
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CLC-2 (YY9) - sc-81871 from Santa Cruz Biotechnology
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Anti-CLCN2 antibody - ab192506 from Abcam
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Anti-CLCN2 antibody - ab130686 from Abcam
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Anti-CLCN2 antibody - ab54664 from Abcam
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Anti-CLCN2 antibody [EPR6492(2)] - ab154798 from Abcam
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Anti-CLCN2 Antibody (C-Terminus) - LS-C6121 from LifeSpan Bioscience
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Anti-CLCN2 Antibody (C-Terminus) - LS-C6122 from LifeSpan Bioscience
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Anti-CLCN2 Antibody (aa38-388, clone 10B2253, Azide-free) - LS-C183520 from LifeSpan Bioscience
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Anti-CLCN2 Antibody (aa208-237, AP) - LS-C254921 from LifeSpan Bioscience
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Anti-CLCN2 Antibody (aa208-237, Biotin) - LS-C254922 from LifeSpan Bioscience
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Anti-CLCN2 Antibody (aa208-237, APC) - LS-C254923 from LifeSpan Bioscience
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Anti-CLCN2 Antibody (aa208-237, FITC) - LS-C254924 from LifeSpan Bioscience
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Anti-CLCN2 Antibody (aa208-237, Azide-free, HRP) - LS-C254925 from LifeSpan Bioscience
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Anti-CLCN2 Antibody (aa208-237, PE) - LS-C254926 from LifeSpan Bioscience
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Anti-CLCN2 Antibody (aa208-237) - LS-C320413 from LifeSpan Bioscience
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Anti-CLCN2 Antibody - LS-C341924 from LifeSpan Bioscience
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Anti-CLCN2 Antibody (aa738-751) IHC-plus™ - LS-B5141 from LifeSpan Bioscience
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Anti-CLCN2 Antibody (Internal) - LS-C112963 from LifeSpan Bioscience
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Anti-CLCN2 Antibody - LS-C334513 from LifeSpan Bioscience
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Anti-CLCN2 Antibody (aa208-237) - LS-C168805 from LifeSpan Bioscience
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Anti-CLCN2 Antibody (clone 3E1) - LS-C196930 from LifeSpan Bioscience
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