CLCN2

Gene Symbol CLCN2
Entrez Gene 1181
Alt Symbol CIC-2, CLC2, ECA2, ECA3, EGI11, EGI3, EGMA, EJM6, EJM8, LKPAT, clC-2
Species Human
Gene Type protein-coding
Description chloride channel, voltage-sensitive 2
Other Description chloride channel 2|chloride channel protein 2
Swissprots B4DQT9 Q6IPA9 O14864 Q8WU13 B4DZ58 P51788 E9PCD2 E9PBD9
Accessions AAB34722 EAW78248 EAW78249 EAW78250 P51788 AA524434 AF026004 AAB88807 AK298952 BAG61051 AK302389 BAG63705 AK302759 BAG63970 AU132760 BC021578 AAH21578 BC072004 AAH72004 BX089717 DB533341 DC403930 XM_006713489 XP_006713552 XM_006713490 XP_006713553 XM_011512401 XP_011510703 XM_011512402 XP_011510704 NM_001171087 NP_001164558 NM_001171088 NP_001164559 NM_001171089 NP_001164560 NM_004366 NP_004357
Function Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. {ECO:0000269|PubMed:19153159, ECO:0000269|PubMed:19191339}.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Ubiquitously expressed. Moderately expressed in aortic and coronary vascular smooth muscle cells and expressed at a low level in aortic endothelial cells. {ECO:0000269|PubMed:10198195}.
Top Pathways Mineral absorption

CLC-2 CRISPR/Cas9 KO Plasmid (h) - sc-403513 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLC-2 HDR Plasmid (h) - sc-403513-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLC-2 Double Nickase Plasmid (h) - sc-403513-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLC-2 Double Nickase Plasmid (h2) - sc-403513-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLC-2 CRISPR Activation Plasmid (h) - sc-403513-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLC-2 CRISPR Activation Plasmid (h2) - sc-403513-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLC-2 Lentiviral Activation Particles (h) - sc-403513-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLC-2 Lentiviral Activation Particles (h2) - sc-403513-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLC-2 siRNA (h) - sc-42379 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLC-2 shRNA Plasmid (h) - sc-42379-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLC-2 shRNA (h) Lentiviral Particles - sc-42379-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLCN2 RNAi - H00001181-R01V from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human
Western Blot: CLCN2 RNAi [H00001181-R01V] - Analysis of CLCN2 over-expressed 293 cell line, cotransfected with CLCN2 Validated Chimera RNAi or non-transfected control. Blot probed with H00001181-M01. GAPDH (36.1 kDa) used as loading control.

MISSION® esiRNA - EHU132911 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6169 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6169 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CLCN2 siRNA (Human) - CRH0843 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CLCN2 RNAi - H00001181-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CLCN2 - MBS8236892 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CLCN2 (NM_004366.5) - SHH264557 from Creative biogene

Category siRNA
Species Reactivities Human

Human CLCN2 siRNA - orb261345 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CLCN2 shRNA Plasmid (Human) - CHH0843 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CLCN2 miRNA 3'UTR clone - MiUTR3H-03483 from Creative biogene

Species Reactivities Human
Search more