| Gene Symbol |
HYPK
|
| Entrez Gene |
25764
|
| Alt Symbol |
C15orf63, HSPC136
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
huntingtin interacting protein K
|
| Other Description |
huntingtin yeast partner K|huntingtin-interacting protein K
|
| Swissprots |
O75408 C9JKJ0 Q9NX55 Q9P024 Q8WUW8
|
| Accessions |
EAW77241 EAW77242 Q9NX55 AF049613 AAC26849 AF161485 AAF29100 AK022435 BC019262 AAH19262 BQ478474 BQ772100 NM_001199885 NP_001186814 NM_016400 NP_057484
|
| Function |
Has a chaperone-like activity preventing polyglutamine (polyQ) aggregation of HTT. Protects against HTT polyQ-mediated apoptosis in Neuro2a neuronal cells. Required for optimal NAA10- NAA15 complex-mediated N-terminal acetylation. {ECO:0000269|PubMed:17947297, ECO:0000269|PubMed:20154145}.
|
| Subcellular Location |
Nucleus. Cytoplasm.
|