Gene Symbol | HYPK |
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Entrez Gene | 25764 |
Alt Symbol | C15orf63, HSPC136 |
Species | Human |
Gene Type | protein-coding |
Description | huntingtin interacting protein K |
Other Description | huntingtin yeast partner K|huntingtin-interacting protein K |
Swissprots | O75408 C9JKJ0 Q9NX55 Q9P024 Q8WUW8 |
Accessions | EAW77241 EAW77242 Q9NX55 AF049613 AAC26849 AF161485 AAF29100 AK022435 BC019262 AAH19262 BQ478474 BQ772100 NM_001199885 NP_001186814 NM_016400 NP_057484 |
Function | Has a chaperone-like activity preventing polyglutamine (polyQ) aggregation of HTT. Protects against HTT polyQ-mediated apoptosis in Neuro2a neuronal cells. Required for optimal NAA10- NAA15 complex-mediated N-terminal acetylation. {ECO:0000269|PubMed:17947297, ECO:0000269|PubMed:20154145}. |
Subcellular Location | Nucleus. Cytoplasm. |
Recombinant Human HYPK - HYPK-1156H from Creative Biomart
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Recombinant Human Huntingtin-interacting protein K(HYPK) - CSB-YP885751HU CSB-EP885751HU CSB-BP885751HU CSB-MP885751HU from Cusabio
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Huntingtin interacting protein K (HYPK) - TP300840 from Acris Antibodies
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Huntingtin Interacting Protein K Recombinant Protein Antigen - NBP2-49177PEP from Novus Biologicals
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HYPK Peptide, Human - M34GP07372H from Creative Peptides
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Huntingtin-interacting protein K (HYPK), Recombinant Protein - MBS1385920 from MyBioSource
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